摘要
目的：介绍微电极记录技术在治疗帕金森病中的作用。方法：采用微电极细胞电生理记录技术进行术中靶点监测，对１００例帕金森病患者行苍白球腹后部（９６例）和丘脑腹外侧核（４例）毁损术，患者术前及术后评估采用ＵＰＤＲＳ积分，术中靶点更换率为８７％。结果：手术效果优良，有效率１００％，原有症状术后显著改善率平均达８９．４％，无永久并发症。结论：微电极的应用能显著减少手术并发症的发生，提高手术效果。
Objective: To introduce the role of microelectrode recording in operation for Parkinson's disease. Methods:One hundred patients underwent pallidotomy and thalamotomy for Parkinson's disease by means of microelectrode recording used as intraoperative target localization between Oct. 1997 and Apr. 1998. The patients were assessed by means of UPDRS. Results: The change rate of targets is 87% and the outcome is excellent, every patient shows improvement and obvious relief of symptoms is about 874%. No patient shows permanent complication. Conclusion: The author regards microelectrode recording can decrease the rate of complication and give a better outcome.
出处
《中华神经外科杂志》
CSCD
北大核心
1998年第4期202-205,共4页
Chinese Journal of Neurosurgery
关键词
震颤性麻痹
外科手术
微电极记录
Parkinson's disease Microelectrode recording Stereotaxy Operation
