摘要
目的 对震颤、僵硬及运动迟缓帕金森病 (PD)患者的立体定向手术方法进行探讨。方法 应用微电极导向技术 ,对 86例PD患者行同侧丘脑腹外侧核及苍白球腹后部同期毁损手术。结果 86例PD患者的肢体震颤、僵硬及运动迟缓均得到明显改善 ,术前术后MotorUPDRS积分开状态及关状态均有显著提高 (P <0 0 1) ,无永久并发症。结论 应用微电极引导立体定向技术 ,对伴有肢体震颤、强直及运动迟缓的PD患者行同侧苍白球腹后部及丘脑腹外侧核联合毁损手术 ,是一种安全有效的手术方法。
Objective To probe the stereotactic operative therapy for Parkinsons disease with tremor, rigidity and bradykinesia.Methods With the help of microelectrode guided technique, ipsilateral thalamotomy and pallidotomy were used for 86 Parkinsonian patients.Results Tremor, rigidity and bradykinesia of all 86 patients were alleviated distinctly. Preoperative and postoperative UPDRS score, “on” and “off” condition improved significantly. No permanent operative complications was foud. Conclusions For Parkinsonian patients with tremor, rigidity and bradykinesia, the microelectrode guided ipsilateral Vim/Vop thalamotomy and posteroventral pallidotomy is a good complementary for thalamotomys ineffective to tremor. The excellent combination of thalamotomy and pallidotomy is a safe and effective surgical therapy, which does not increase the danger of operation and can alleviate symptoms of Parkinsons disease.
出处
《中华神经外科杂志》
CSCD
北大核心
2000年第2期78-81,共4页
Chinese Journal of Neurosurgery
