摘要
目的 :探讨黄芪对失血性休克兔心功能的影响。方法 :16只家兔随机分为 2组 :黄芪组 (HQ)和生理盐水组 (NS)。股动脉放血至平均动脉压降至 5 33kPa(4 0mmHg) ,动态观察黄芪对血流动力学各指标影响。 结果 :与NS组比较 ,治疗期HQ组心率减慢 (P <0 0 5 ) ,平均动脉压 (MAP)、左室压力峰值 (LVSP)和舒张末期压力(LVEDP)迅速上升 (P <0 0 5 ,P <0 0 5 ,P <0 0 5 ) ,左室压力下降最大速率 (-dp/dtmax)和等容舒张期压力下降时间常数 (T值 )显著得到改善 (P <0 0 1,P <0 0 1) ,左室压力上升最大速度 (+dp/dtmax)在血量恢复后才高于NS组 (P <0 0 5 )。结论
OBJECTIVE:To investigate the effects of astragalus on the left Ventricular function after hemorrhaic shock in rabbits. METHOD:Sixteen rabbits were randomly divided into 2 groups:astragalus group (HQ) and normal saline group (NS).Shock was induced with bleeding by femora artery.Effect of astragalus on hemodynamics was observed.RESULTS:Compared with NS group,the results showed that amplitudes of LVSP,LVEDP,±dp/dt max and mean arterial pressure of HQ group increased markedly (P<0 05,P<0 01);while T and heart rate decreased obviously (P<0 01,P<0 05).CONCLUSION:Astragalus could improve the left ventricular systolic and diastolic function significantly.
出处
《九江医学》
2001年第2期63-65,共3页
Jiujiang Medical Journal
