摘要
目的 研究胆石症手术患者 CIC(循环免疫复合物 )、Ig(免疫球蛋白 )、T淋巴细胞亚群和胆石中 Ig G型 IC(免疫复合物 )及细菌的变化。方法 胆石症患者 5 0例 (男 2 0例 ,女 30例 ) ,平均年龄 46岁。术前、术后 5 d测定 CIC、Ig、T淋巴细胞亚群 ,并培养结石细菌。结果 与对照组比较 ,胆结石患者术前血中 CIC(u/L ,5 .3± 1.5 vs 1.2± 0 .8,P<0 .0 1)增高 ,Ig G(g/L ,8.7± 2 .0 vs 11.2± 3.2 ,P<0 .0 5 ) ,CD3+ (% ,5 2± 5 vs 6 6± 10 ,P<0 .0 1) ,CD4+ (% ,2 9± 4vs 44±9,P<0 .0 1)和 CD8+ (% ,2 0± 3 vs 31± 7,P<0 .0 1)则降低 ,但术后恢复正常。胆石中 IC阳性率为 82 % ,细菌培养阳性率为 85 % ,主要是大肠杆菌。结论 胆石症术前、术后血 CIC、Ig G、T淋巴细胞亚群均有明显的改变 ,结石中 IC阳性率高 ,培养主要为大肠杆菌。
Objective To analyse blood circulation immune complexes (CIC),immunoglobulin(Ig) and T lymphocyte subpopulation,and immune complexes(IC) and bacteria cultured of gallstone IgG in patients with cholecystectomy.Methods Plasma levels of CIC,IgA,IgM,CD3,CD4 and CD8,and gallstone special IgG were measured,and gallstone bacteria cultured in 50 patients(20 men,30 female)with pre operation and post operation on 5 days for cholecystectomy,the mean age was 46 years.Results Plasma CIC(U,5.3±1.5vs 1.2±0.8,P<0.01) was significantly higher,and IgG(g.L -1 ,8.7±2.0vs 11.2±3.2,P<0.05),CD3+(%,52±5 vs 66±10,P<0.01),CD4+(%,29±4 vs 44±9,P<0.01) and CD8+(%,20±3 vs 31±7,P<0.01) were lower in patients with pre operation than that of controls,and their chages got right in the post operation.Positive IC was 82 percent and positive rate of bacteria cultured was 85 percent in the gallstone.Conclusions Plasma CIC,IgG and T lymphocyte subpopulation were changes in patients with cholecystectomy,but got right in the post operation,and there were positive IC and bacteria in the gallstone.
出处
《中国误诊学杂志》
CAS
2001年第5期654-656,共3页
Chinese Journal of Misdiagnostics
