摘要
乙型肝炎病毒相关性肾炎(HBV-GN)属继发性肾小球病,其发病机制包括循环免疫复合物损伤、细胞免疫、病毒直接作用及自身免疫性因素等,常见病理类型为膜性肾病(MN)、膜增生性肾小球肾炎(MPGN)、IgA肾病(IgAN)及系膜增生性肾小球肾炎(MsPGN)等。本文综述HBV-GN的流行病学、发病机制、临床表现和治疗等方面的研究进展。
Hepatitis B virus associated glomerulonephritis (HBV-GN)is one of the secondary glomerulopathies with the clinical manifestation of liver and kidney injury, the pathogenesis of which includes circulating immune complex (CIC)injury, cell immunity, HBV coup injury, autoimmunity and genetic factor. Frequent pathological types of HBV-GN include membranous nephropathy (MGN), membrane proliferative glomerulonephritis (MPGN), IgA nephropathy (IgAN) and mesangial proliferative glomerulonephritis (MsPGN). This article summarized the advancements of HBV-GN in pathogenesis, diagnosis and treatment.
出处
《世界临床药物》
CAS
2009年第6期339-344,共6页
World Clinical Drug
关键词
肾炎
乙型肝炎病毒
发病机制
诊断
治疗
nephritis
hepatitis B virus
pathogenesis
diagnosis
treatment