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核因子-E2相关因子2在溃疡性结肠炎中的表达及其与氧化应激的关系 被引量:5

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摘要 UC病程长,易癌变,发病率逐年增高,发病机制尚不明确.有研究显示,UC发生与氧化应激有关[1-4].核因子-E2相关因子2(nuclear factor-E2 related factor 2,Nrf2)对外源性毒物和体内的氧化应激敏感,在氧化应激中发挥重要作用.Nrf2与肺纤维化、白血病、肾病、心肌梗死、脑出血等疾病均有关.有关Nrf2基因型的研究亦有报道[5].本研究旨在探讨Nrf2蛋白表达及其与氧化应激的关系.
出处 《中华消化杂志》 CAS CSCD 北大核心 2014年第6期401-403,共3页 Chinese Journal of Digestion
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