摘要
目的探讨丹参、川芎嗪联合高压氧治疗对脑梗死患者神经功能及血液流变学的影响。方法将124例急性脑梗死患者随机分为观察组和对照组,各62例。两组患者均给予丹参、川芎嗪静滴治疗,观察组联合高压氧治疗。观察两组患者临床疗效、神经功能缺损评分及血液流变学的变化。结果观察组治疗总有效率88.71%,高于对照组的69.35%(P<0.01);观察组治疗后血液流变学3项指标均较治疗前降低(P<0.01);对照组治疗后血浆高切粘度、全血高切粘度较治疗前降低(P<0.01);治疗后观察组血液流变学各指标均低于对照组(P<0.05或P<0.01)。结论丹参、川芎嗪联合高压氧治疗脑梗死能有效改善神经功能及血液流变学指标,提高治疗效果。
Objective To investigate effect of salvia miltiorrhiza,ligustrazine injection adjuvant hyperbaric oxygen on nerve function and hemodynamics in patients with cerebral infarction. Methods One hundred and twenty-four patients with acute cerebral infarction were divided into observation group and control group,and the two groups were given salvia miltiorrhiza,ligustrazine injection therapy,and observation group was given combined therapy of hyperbaric oxygen. Clinical curative effect,neural function defect scale and hemodynamics were compared. Results Observation group＇s total efficiency rate was 88. 71%,higher than 69. 35% of control group（ P〈0.01）. The three indexes of hemodynamics in observation group after treatment were lower than these before treatment（ P〈0.01）,but high shear viscosity,whole blood high shear viscosity,whole blood low shear viscosity and fibrinogen of control group after treatment were lower than these before treatment（ P〈0.01） and indexes of hemodynamics in observation group after treatment were lower than these of control group（ P〈0.05 or P〈0.01）. Conclusion Salvia miltiorrhiza,ligustrazine injection combined with hyperbaric oxygen treatment of cerebral infarction can effectively improve nerve function and hemodynamics.
出处
《白求恩医学杂志》
2014年第3期234-235,共2页
Journal of Bethune Medical Science
关键词
丹参
川芎嗪
高压氧
血液流变学
Salvia miltiorrhiza
Ligustrazine
Hyperbaric oxygen
Hemodynamics
