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噬血细胞综合征的实验室诊断及临床分析 被引量:7

Clinical analysis and laboratory diagnosis of hemophagocytic syndrome
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摘要 目的探讨噬血细胞综合征(HPS)的临床特征、实验室检查及骨髓细胞形态特点。方法对16例确诊为HPS患者的临床症状、体征、实验室检查及骨髓细胞形态进行分析。结果 16例患者均有发热和不同程度的肝、脾、淋巴结肿大及肝功能异常,外周血细胞减少,骨髓涂片均可见组织细胞增生并伴有吞噬血细胞现象。结论 HPS的临床特征实验室检查和骨髓细胞形态具有一定的普遍性和特异性,有助于临床诊断。 [Objective ] To investigate the clinical symptom, laboratory data and the morphology of bone marrow cells of hemophagocytic syndrome (HPS). [Methods ] The clinical symptoms, physical signs, laboratory examinations and morphology of bone marrow cells of 16 HPS patients were collected and analyzed. [ Results ] All the 16 patients had fever, hepatomegaly, splenomegaly, lymphadeneetasis, hepatic dysfunction and peripheral blood cells diminution. While histocyte hyperplasia with active hemophagocytic phenomenon was found in all the bone marrow slides. [ Conclusions ] The clinical features, laboratory data ard morphology of bone marrow cells of HPS are universal and specific, which is beneficial to clinical diagnosis.
出处 《中国现代医学杂志》 CAS CSCD 北大核心 2014年第7期32-35,共4页 China Journal of Modern Medicine
关键词 噬血细胞综合征 临床特征 实验室检查 骨髓细胞形态 hemophagocytic syndrome clinical symptom laboratory data bone marrow cells
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