摘要
噬血细胞综合征(HPS)又称为噬血细胞性淋巴组织细胞增生症,是一种病理性免疫激活引起过度炎症反应的临床综合征,临床分为继发性和原发性。由于病因多,发病机制复杂,临床表现多样化,诊断难度大,漏诊、误诊的可能性大。本文就HPS的病因、发病机制、诊断及治疗等方面的研究进展进行综述,以期为临床诊治HPS提供一定的理论依据。
Hemophagocytic syndrome(HPS),also known as hemophagocytic lymphohistiocytosis,is a clinical syndrome in which pathological immune activation causes excessive inflammatory response,clinically divided into secondary and primary.Due to many causes,the pathogenesis is complicated,the clinical manifestations are diversified,the diagnosis is difficult,and the possibility of missed diagnosis and misdiagnosis is high.This article reviews the research progress in the etiology,pathogenesis,diagnosis and treatment of HPS,in order to provide a theoretical basis for clinical diagnosis and treatment of HPS.
作者
张婷
ZHANG Ting(Department of Hematology,Tianjin Children's Hospital,Tianjin 300000,China)
出处
《医学信息》
2019年第22期46-48,共3页
Journal of Medical Information
关键词
噬血细胞综合征
免疫
炎症反应
Hemophagocytic syndrome
Immunity
Inflammatory response
