摘要
目的通过对真菌性鼻-鼻窦炎(Fungal sinusitis,FRS)与慢性鼻-鼻窦炎(chronic rhinosinusitis,CRS)患者局部骨质及CT值的研究,了解其病变特征和发生、发展及转归,为FRS的手术提供临床的依据。方法选取临床上FRS、CRS患者各30例,非鼻-鼻窦炎患者20例作为对照组。术前CT检查对其值测算。术中对于鼻窦炎患者切除筛骨,送病理检查,得出病理评分。然后比较病理评分及CT值;并分析二者的相关性。结果 FRS筛骨的CT值随筛骨病理等级的增高明显增高;FRS筛窦骨组织的病理等级高于CRS患者;CRS患者CT值高于非鼻-鼻窦炎患者,FRS患者CT值高于CRS患者。结论 FRS及CRS患者中均有一部分患者存在筛骨病变,这种病变包括筛骨黏膜增厚、骨吸收、骨破坏、炎性细胞的浸润以及新骨形成。且FRS筛骨病理等级高于CRS。FRS及CRS患者筛骨CT值与病变范围和筛骨病理分级显著相关,可客观评价患者筛骨病变程度。
Objective The present work aims to study the local bones and CT values of patients with FRS and those with CRS and investigate the characteristics ,occurrence ,development and outcomes of the disease so as to pro-vide certain basis for FRS surgery .Methods 60 patients were selected with FRS and CRS （30 cases each） clinical-ly ,and 20 patients with non-sinusitis as the control group .A preoperative CT examination was conducted on the pa-tients to obtain CT values .The ethmoid bones of patients with nasosinusitis were removed during operation and sent for pathology ,and the histological scores were obtained .Then the scores and CT values were compared .The relevant statistical approach was applied to analyze the relationship between them .Results The CT value of ethmoid bone in patients with CRS increased with the increase of the pathological grade of ethmoid bone .The pathological grade of ethmoid bone tissue in patients with FRS was higher than those with CRS .The CT value of patients with CRS was higher than those with non-sinusitis ,and that of patients with FRS higher than those with CRS .Conclusion Some of the patients with FRS and CRS respectively suffer from ethmoid bone lesions which includes mucosal thickening of ethmoid bone ,bone resorption ,bone destruction ,infiltration with inflammatory cells and new bone formation .Be-sides ,the pathological grade of ethmoid bone in patients with FRS is higher than those with CRS .The CT values and lesions range of patients with FRS and CRS are significantly associated with pathological grading of ethmoid bone .An objective evaluation on the extent of ethmoid bone disease in patients can be performed to provide the basis for prog-nosi s .
出处
《济宁医学院学报》
2014年第2期103-105,共3页
Journal of Jining Medical University
