摘要
目的:观察麻杏石甘汤治疗社区获得性肺炎肺热型的临床疗效及对血清降钙素原(PCT)的影响。方法:将100例社区获得性肺炎患者随机分为治疗组51例、对照组49例,治疗组予基础治疗+麻杏石甘汤每次100mL,每日2次口服;对照组予基础治疗。治疗10d后评价两组临床疗效并监测PCT的变化。结果:两组总疗效、中医证候疗效、总满意率比较,差异有统计学意义(P<0.05,P<0.01),治疗组优于对照组。治疗组体温稳定时间,咳嗽、气急、双肺啰音消失天数,平均治愈天数,X线示炎症吸收天数与对照组比较,差异有统计学意义(P<0.01,P<0.05),治疗组疗效优于对照组。治疗后治疗组中医证候部分指标积分,治疗后5d血常规中白细胞、血PCT与对照组比较,差异有统计学意义(P<0.05,P<0.01),治疗组疗效优于对照组。结论:麻杏石甘汤治疗社区获得性肺炎肺热型疗效肯定,患者满意度高,且对PCT有明显降低作用。
Objective： To observe the efficacy evaluation of Maxing Shigan Decoction on community acquired pneumonia （CAP） and its influence on serum procalcitonin. Methods： A total of 100 CAP patients were randomly divided into a treatment group （51 cases） and a control group （49 cases）. The treatment group was treated with basic therapy and 100mL of Maxing Shigan DecoCtion twice a day, while the control group was treated with basic therapy. After treatment for 10 days, the clinical efficacies of two groups were evaluated and the changes of serum procalcitonin were monitored. Results： Compared the treatment group with the control group, the total efficiency rate, the efficiency rate of TCM syndrome, the total satisfaction rate were statistically significantly different （P〈0.05, P〈0.01）, and the treatment group was superior to the control group. After treatment, time needed for body temperature to stabilize, the number of the days needed for coughing, shortness of breath, and rale to disappear, the average number of the days to cure, and the number of inflammation absorption days （shown with X line） had statistical significance between the two groups （P〈0.01, P〈0.05）, and the treatment group was superior to the control group. After treatment, the Chinese medicine symptom scores, WBC and PCT were better in the treatment group and they had statistical significance between the two groups （P〈0.05, P〈0.01）. The treatment group was superior to the control group. Conclusion： Maxing Shigan Decoction has a curative effect on CAP and it could decrease serum procalcitonin markedly. Patients are highly satisfied with this prescription.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2014年第4期1272-1275,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
关键词
社区获得性肺炎
麻杏石甘汤
临床疗效
降钙素原
, Community acquired pneumonia
Maxing Shigan Decoction
Therapeutic effect
Serum procalcitonin
