摘要
目的了解泌尿生殖系统支原体感染情况,感染人群中性别的分布及对9种抗菌药物的敏感性。方法采用法国梅里埃公司生产的解脲脲原体(Uu)和人型支原体(Mh)培养鉴别定量药敏试剂盒(IST2),对1122例样本进行采集、培养、鉴定和药敏测定。结果 1122例泌尿生殖道感染患者支原体阳性600例,感染率为53.5%;其中解脲支原体感染率39.8%,人型支原体感染率0.5%,Uu合并Mh感染率13.2%;男女性别感染率分别为61.1%(542/887)和24.7%(58/235),经统计学处理,两者差异有统计学意义(P<0.05),药敏结果表明,原始霉素、交沙霉素、多西环素、四环素敏感度明显高于其他抗菌药物。结论支原体对各种抗菌药物已产生一定的耐药性,在治疗支原体感染时应参考药敏结果,如不能做药敏试验,交沙霉素可作为治疗支原体感染的首选药物。
OBJECTIVE To investigate the non-gonococcus urethritis （NGU） caused by Mycoplasma and theirdifference by sex as well as the sensitivities to the 9 antimicrobials. METHODS The mycoplasmaIST2 reagent kit produceted by BioMerieux. sa was adopted, totally 1122 specimens in the patients of NGU were collected, cultured and tested for drug sensitivity. RESULTS Among the 1122 samples,600 were positive（53.5% ） ,which were com- posed by Uu 39.8% ,Mh 0. 5% ,and Uu-Mh infection 13.2%. In 887 females,542 were positive（61.1% ） ,in 235 males,58 were positive （24.7% ;females were more apt to be infected according to statistics （P 〈 0. 05 ）. According to drug sensitivity test results ,pristinamycin ,Josamycin,doxycyline and tetracycline were more sensitive than the oth- er antibiotics. CONCLUSION Mycoplasma has developed resistance to antibiotics already. They should be rational- ly chosen and used according to the drug susceptibility. If drug sensitivity test cannot be done, Josamycin can be used as the preferred drugs.
出处
《海峡药学》
2014年第2期91-94,共4页
Strait Pharmaceutical Journal
关键词
泌尿生殖道
支原体感染
药敏试验
Non-gonococcus urethritis
Mycoplasma infection
Drug sensitivity test
