摘要
目的:探讨多西环素联合盆腔炎2号方治疗支原体感染盆腔炎疗效及安全性分析。方法:选择2015年1月—2016年6月期间于医院就诊收治的支原体感染盆腔炎患者80例为研究对象,根据随机数字表法将两组患者均分为观察组与对照组各40例,其中对照组患者单独给予多西环素治疗,观察组患者在对照组的基础上联合应用盆腔炎2号方治疗,常规治疗后比较两组患者的临床治疗效果、治疗期间的不良反应情况以及患者子宫血流动力学指标指标之间的差异情况。结果:两组患者治疗后,其中观察组患者的临床治愈患者例数27例、治愈率67.5%,明显的高于对照组患者的19例、47.5%,两组比较差异有统计学意义(P<0.05),可以比较;观察组患者的临床治疗无效例数1例、无效率2.5%,明显的低于对照组患者的6例、15.0%,两组比较差异有统计学意义(P<0.05),可以比较;观察组患者治疗期间头晕头痛患者2例、恶心呕吐2例、腹泻0例、肝功能异常1例,明显的低于对照组患者的头晕头痛患者5例、恶心呕吐4例、腹泻5例、肝功能异常3例,两组比较差异有统计学意义(P<0.05),可以比较;观察组患者的阻力指数(RI)0.86±0.03、搏动指数(PI)2.49±0.09以及平均血流速度(Vmin)0.60±0.03,明显的高于对照组患者的阻力指数(RI)0.80±0.02、搏动指数(PI)2.20±0.06以及平均血流速度(Vmin)0.41±0.02,两组比较差异有统计学意义(P<0.05),可以比较。结论:多西环素联合盆腔炎2号方在支原体感染盆腔炎的临床治疗过程中,具有较好的临床治疗效果以及安全性,治疗期间的药物不良反应情况发生率低,可以有效地改善患者的血流动力学指标,在临床上具有极高应用价值,值得进一步推广使用。
Objective：To explore the efficacy and safety of azithromycin combined with pelvic inflammatory disease No.2 Formula in treatment of mycoplasma infection pelvic inflammatory disease.Methods：Eighty cases with mycoplasma infection pelvic inflammatory disease during January 2015 to June 2016 in our hospital were as research object and divided into observation group and control group according to the random number table method,40 cases in each group.The control group was treated with azithromycin alone and the patients in the observation group were treated with pelvic inflammatory disease No.2 Formula on the basis of the control group.The difference of the clinical therapeutic effect,adverse reaction during treatment,and uterine hemodynamics in two groups were compared after treatment.Results：After treatment of two groups,among them 27 patients were cured in the observation group,and the cure rate was 67.5%,significantly higher than 19 patients,47.5% of the control group.The difference between the two groups was statistically significant（P〈0.05）.One case was clinical ineffective in the observation group and the inefficiency was 2.5%,significantly lower than 6 patients and 15% of the control group.The difference between the two groups was statistically significant（P〈0.05）.There were 2 cases of dizziness and headache,2 cases of nausea and vomiting,0 case of diarrhea,and 1 case of abnormal liver function in observation group during treatment,significantly lower than 5 cases of dizziness headache,4cases of nausea and vomiting,5 cases of diarrhea,3 cases of abnormal liver function in the control group.The difference between the two groups was statistically significant（P〈0.05）.Resistance index（RI）,pulsatility index（PI） and mean blood flow velocity（Vmin） in the observation group were 0.86±0.03,2.49±0.09 and 0.60±0.03,significantly higher than those（0.80±0.02,2.20±0.06,0.41±0.02） in the control group.The difference between the two groups was statistically significant（P〈0.05）
出处
《中华中医药学刊》
CAS
北大核心
2017年第8期2145-2148,共4页
Chinese Archives of Traditional Chinese Medicine
基金
海南省卫计委项目(1421320.31A2004)
关键词
盆腔炎
支原体感染
多西环素
盆腔炎2号方
pelvic inflammatory disease
mycoplasma infection
azithromycin
pelvic inflammatory disease No.2 Formula
