摘要
目的：分析木村病的临床特点，探讨木村病的诊治方法及预后。方法：检索《万方数据》2001—2011年木村病的病例报道49例，对其临床表现、实验室检查、治疗及预后进行综合分析。结果：木村病主要表现为头颈部肿块、淋巴结肿大、大涎腺侵犯，可合并肾病综合征，外周血嗜酸性粒细胞计数增多、血清IgE水平升高，双链DNA均阴性，病灶边界不清无包膜，糖皮质激素治疗有效，但易复发。有2例患者转化为恶性淋巴瘤。结论：木村病是一种病因未明、常累及周围淋巴结、大涎腺和肾脏的慢性炎症性疾病，糖皮质激素治疗有效但容易复发，有向恶性淋巴瘤转化的倾向。
Objective：To review the clinical features of Kimura disease and investigate its diagnosis, therapy and prognosis. Methods： The clinical manifestation, laboratory examination, therapy and prognosis of 49 patients with Kimura disease searched by Wanfang database from 2001 to 2011 were analyzed. Results： Head and neck neoplasm, swelling lymph nodes and large salivary gland involvement complicating with nephrotic syndrome were the clinical features of the Kimura disease. The increasing peripheral eosinophil count,the rising serum IgE level and the negative double-stranded DNA were found. The lesion boundary was not clear and no envelope. The glucocorticoid therapy was effective, but easy to relapse. Two patients transformed into malignant lymphoma. Conclusions： The cause of Kimura disease is unknown. It is a chronic inflammatory disease complicated with kidney chronic inflammation. The peripheral lymph nodes and large salivary glands are often involved. The glucocorticoid therapy is effective, but easy to relapse. Kimura disease has the tendency of transforming into malignant lymphoma.
出处
《蚌埠医学院学报》
CAS
2014年第2期184-186,共3页
Journal of Bengbu Medical College
关键词
木村病
临床表现
治疗
Kimura diease
clinical manifestation
therapy
