摘要
猪繁殖与呼吸综合征(porcine reproductive and respiratory syndrome,PRRS)一直是危害世界养猪业较严重的疾病,给世界养猪业造成巨大经济损失。其病毒感染机理、抗体依赖性增强(ADE)作用及高度变异性使目前的商品化疫苗存在着缺陷,不能完全阻止经呼吸系统及胎盘传播猪繁殖与呼吸综合征病毒(porcine reproductive and respiratory syndrome virus,PRRSV)。鉴于此,应结合PRRSV的致病特点、免疫特性及生物学特性探索性地设计新型疫苗,对预防该病具有重要意义。
Porcine reproductive and respiratory syndrome is a serious disease, causing significantly economical impacts on the swine industry worldwide. Because of the mechanism of virus infection, the characteristics of antibody-dependent enhance- ment and a high degree of variability, the commercial vaccines currently exist defects that can＇t completely prevent the respira tory system and placental transmission of porcine reproductive and respiratory syndrome virus （PRRSV）. Therefore, according to the pathogenic characteristics, PRRSV immune characteristics and biological characteristics, the new vaccines are designed which have important significances to the prevention of the disease.
出处
《中国畜牧兽医》
CAS
北大核心
2014年第2期239-244,共6页
China Animal Husbandry & Veterinary Medicine
关键词
猪繁殖与呼吸综合征病毒
危害
免疫
porcine reproductive and respiratory syndrome virus
harm
immunization
