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吡贝地尔治疗一氧化碳中毒迟发性脑病所致的肌张力障碍的疗效观察 被引量:2

Effect observation of piribedil in the treatment of dystonia in patients with delayed encephalopathy caused by carbon monoxide poisoning
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摘要 目的观察吡贝地尔治疗一氧化碳中毒迟发性脑病所致的肌张力障碍的效果。方法 100例患者随机分为观察组和对照组各50例,对照组给予常规治疗,观察组在对照组基础上应用吡贝地尔。观察临床疗效。结果观察组总有效率为98%高于对照组的90%,显效时间为(14.2±1.4)h短于对照组(33.0±8.0)h,差异有统计学意义(P<0.05)。结论吡贝地尔可以较好地改善一氧化碳中毒迟发性脑病所致的肌张力障碍;早期联合应用吡贝地尔可显著提高患者生活质量。 Objective To observe the effect observation of piribedil in the treatment of dystonia in patients with de- layed encephalopathy caused by carbon monoxide poisoning. Methods 100 cases of patients were divided into observation group and control group, each of 50 cases. The control group was given conventional treatment, while the observation group was given piribedil based on the control group. The clinical effect of 2 groups was observed. Results The total effective rate of the observation group was 98% ,which was higher than that of the control group;the effective time of the observation group was ( 14.2± 1.4) h, which was shorter than (33.0 ±8.0 ) h of the control group, and the differences were statistically significant (P 〈0. 05 ). Conclusion Piribedil can be used to improve dystonia caused by the delayed encephalopathy of carbon monox- ide poisoning,and the early application of which can significantly improve the quality of life of the patients.
出处 《临床合理用药杂志》 2014年第2期7-8,共2页 Chinese Journal of Clinical Rational Drug Use
关键词 一氧化碳中毒 迟发性脑病 多巴胺受体激动剂 吡贝地尔 Carbn monoxide poisoning Chronic encephalopathy Dopamine receptor agonist Piribedil
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