摘要
目的探讨慢性荨麻疹发病与血清中食物特异性IgG抗体的关系。方法应用酶联免疫吸附试验(ELISA)检测111例慢性荨麻疹患者(慢性荨麻疹组)血清中食物特异性IgG抗体水平,并与30例健康受试者(对照组)资料进行对比研究。结果 111例慢性荨麻疹患者中,食物特异性IgG抗体阳性79例(阳性率为71.17%),与对照组阳性率(43.33%)比较,差异有统计学意义(χ2=8.071,P<0.01)。且慢性荨麻疹组以鸡蛋特异性IgG抗体阳性率最高(51.35%),其次是虾(43.24%)、牛奶(38.74%)、螃蟹(34.23%)、大豆(27.93%),慢性荨麻疹组鸡蛋、虾、螃蟹、鳕鱼、大豆特异性IgG抗体阳性率与对照组比较,差异有统计学意义(P<0.05)。结论食物特异性IgG抗体与慢性荨麻疹发病具有相关性,血清食物特异性IgG水平检测对慢性荨麻疹的预防和治疗具有重要意义。
Objective To explore the relationship between specific immunoglobulin G（IgG） antibody from serum food and chronic urticaria. Methods Enzyme linked immunosorhent assay （ELISA） was applied to detect the food-specific IgG antibody level in serum of 111 patients with chronic urticaria （chronic urticaria group ）, and 30 healthy people （control group ） were se- lected for comparative study. Results Among the 111 eases of chronic urticaria, 79 cases were with positive food-specific IgG antibody in serum with the positive rate of 71.17%, comparing with the positive rate in control group （43.33%）, the difference had statistical significance （X2=8.071, P〈0.01 ）. In chronic urticaria group, the highest positive rate （51.35% ） appeared in the egg test, followed by shrimp （43.24%）, milk （ 38.74% ）, crab （ 34.23% ） and soybean （27.93%）. Compared with the control group, the positive rate of specific IgG antibody in egg, shrimp, crab, cod and soybean in chronic urticaria group had statistically signifi- cant difference （P〈O.05）. Conclusion Food-specific IgG antibody has a relationship with chronic urticaria, and it is important to detect food-specific IgG level in serum to improve the prevention and treatment of chronic urticaria.
出处
《现代医药卫生》
2014年第1期8-10,共3页
Journal of Modern Medicine & Health
关键词
酶联免疫吸附测定
免疫球蛋白G
分析
敏感性与特异性
皮肤疾病
食物过敏
慢性病
荨麻疹
血清
食物不耐受
Enzyme-linked immunosorbent assay
Immunoglobulin G/analysis
Sensitivity and specificity
Skin diseases
Food hypersensitivity
Chronic disease
Urticaria
Serum
Food intolerance
