摘要
目的：探讨小儿Ⅱ度烧伤的治疗方法及疗效。方法将2012年1月～2013年7月以来收治的68例Ⅱ度烧伤患儿分为治疗组及对照组，治疗组使用贝复济（外用重组牛碱性成纤维细胞生长因子）联合复方磺胺嘧啶锌凝胶凡士林纱布换药治疗，对照组用磺胺嘧啶银乳膏纱布换药，比较两组治疗效果。结果治疗组与对照组相比，患儿创面愈合时间缩短，具有统计学意义（P＜0.05），患儿舒适度提高、创面渗出减少，细菌检出率无统计学意义（P＞0.05）。治疗期间所有患儿实验室检测指标与药物不存在明显相关。结论贝复济联合复方磺胺嘧啶锌凝胶凡士林纱布治疗小儿Ⅱ度烧伤，有效缩短创面愈合时间，提高患儿舒适度，减少创面渗出，抑菌效果与磺胺嘧啶银乳膏相当，且治疗期间患儿未出现不良反应，治疗效果较好，值得临床推广。
Objective To study the clinical efficacy of treatment of Ⅱ burn wound in children. Methods Sixty-eight children with Ⅱ burn wound in the hospital from Jan.2012 to Jul.2013 were randomly divided into treatment group and control group. Patients in treatment group were covered with BFGF（recombinant bovine basic fibroblast growth factor） combined compound sulfadiazine zinc pingment gel with vaseline gauze, and those in the control group were treated with sulfadiazine silver cream. The effect of the treatment was compared between two groups. Results Compared with the control group, the treatment group exhibited a significantly shorter wound healing time, higher levels of fitness and lower seepage amount（P〈0.05）; but there was no statistical significance about bacteria detection rate （P 〉 0.05）. We also found there was no direct relationship between the laboratory abnormalities and the therapeutic measures during the study. Conclusion BFGF combined compound sulfadiazine zinc pingment with gel with vaseline gauze can shorten the wound healing time, improve levels of fitness, reduce seepage amount, and the antibacterial effect is better than sulfadiazine silver cream. And it shows no noticeable adverse effect, so it was worth of clinical application.
出处
《中国医药科学》
2013年第23期112-113,138,共3页
China Medicine And Pharmacy
