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胎儿脐静脉管壁细胞核密度的形态定量研究 被引量:4

A Morphological Quantitative Analysis of Cell Nuclear Density in Walls of Human Umbilical Cord Vein
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摘要 目的 :探讨胎儿脐静脉随胎龄变化的形态学。方法 :选取 33例 32~ 42周的新鲜脐带 ,横断取材 ,常规石蜡包埋、切片、染色、光镜观察、计算机图像定量分析。结果 :随胎龄的增长 ,脐静脉管径与中膜厚度逐渐增大 ,中膜平滑肌含量逐渐增多 ,但 40周以后呈下降态势。中膜平滑肌细胞核的数密度和面密度在 37~ 40周最大。结论 :脐静脉管壁中膜平滑肌含量与细胞核的数密度和面密度随胎龄增加而增多 ,建议选用胎龄在 37~ 40周之间的脐静脉作为移植材料。 Objective To study the age-specific morphology of fetal umbilical vein and to provide evidence for clinical wide use. Methods Fresh umbilical veins obtained from 33 cases of 32-42 weeks old were sliced with paraffin section methods. The section preparations stained with HE and special methods was measured using light microscope and image analysis system. Results Umbilical vein wall, media membrane, and smooth muscle widened with age. The cellular nuclear numerical density(CNND)and the cellular nuclear area density(CNAD)are the greatest at the age of 37-40 weeks.Conclusion The smooth muscle, CNND and CNAD are increased with fetal age, suggesting that it is advisable for the choice of 37~40-week-old umbilical vein as grafts.
出处 《郧阳医学院学报》 2000年第4期205-207,共3页 Journal of Yunyang Medical College
关键词 脐静脉 胎儿 细胞核密度 形态结构 umbilical vein tunica intima muscle,smooth,vascular karyometry Image processing,computer-assisted
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