摘要
目的:探讨针灸分期治疗促进骨折愈合的作用机理。方法:将90例患者随机分为针灸三期组、常规针刺组、药物组,每组30例。3组均常规应用抗生素抗感染治疗,均治疗56天,分别于入院1、28、56天取血进行生化指标检测,并观察14、28、56天时的骨痂生长情况(X线片)。结果:骨折愈合过程中,28天时针灸三期组血清钙显著高于同时间点常规针刺组和药物组(P<0.01),28、56天时针灸三期组血清磷浓度均高于同时间点常规针刺组和药物组(P<0.05),28天时针灸三期组ALP活性高于同时间点常规针刺组和药物组(P<0.05);针灸三期组14、28、56天时X线骨痂评分明显高于同时间点常规针刺组和药物组(P<0.05)。结论:针灸分期治疗促进骨折愈合的机理可能是:提高血清钙、磷含量,促进钙磷沉积;提高血清ALP的活性,增强机体内成骨活动。
Objective: To further explore the treatment effect of acupuncture based on different stages on fracture and promoting healing effect.Methods: 90 patients with distal tibial fracture were randomly divided into acupuncture based on different stages group,routine acupuncture group and control group( medicine),each group contained 30 cases,the three groups were given the routine application of antibiotics to prevent infection,they were treated for 56 days. Taking blood to determine serum calcium,phosphorus and alkaline phosphatase on the second,28th and 56th day after being hospitalized,observing the bony callus growth on the 14th,28th and 56th day.Results: The serum calcium concentration of acupuncture based on different stages group was significantly higher than that in routine acupuncture group and medicine group on the 28th day during the fracture healing,the serum phosphorus concentration of acupuncture based on different stages group was obviously higher than that in the other two groups on the 28th and 56th day at the same time,the serum alkaline phosphatase activity of acupuncture based on different stages group was higher than that in routine acupuncture group and medicine group on the 28th day,the radiographic callus score of acupuncture based on different stages group was significantly higher than that in the other groups on the 14th,18th and 56th day.Conclusion: Acupuncture based on different stages can promote fracture to heal by raising serum calcium,phosphorus content and enhancing serum alkaline phosphatase activity.
出处
《中国中医药科技》
CAS
2013年第5期447-448,439,共2页
Chinese Journal of Traditional Medical Science and Technology
基金
湖南省科学技术厅科技计划基金资助项目No.2010SK3181
