摘要
近来研究发现氧化应激产生的活性自由基是与葡萄膜炎发生相关的细胞因子和趋化因子的必须介质.氧化应激在非感染性和感染性葡萄膜炎发生和发展中均起了关键作用,调节或控制氧化应激有助于改善葡萄膜炎的症状.各种抗氧化剂通过不同的作用机制,如抑制氧化应激的产生,减少氧化应激的损伤,增强机体自身的抗氧化功能,达到治疗葡萄膜炎的目的.抗氧化治疗将可能是葡萄膜炎治疗的新策略.
Active free radicals produced following the oxidative stress have been found recently to be a requisite medium of cytokines and chemokines associated with uveitis.Oxidative stress plays a key role in infectious and non infective uveitis.Regulating or controlling oxidative stress could alleviate the symptoms of uveitis.Various antioxidants treat uveitis through different mechanisms,such as inhibiting oxidative stress,reducing oxidative stress damage or enhancing antioxidant capability of the organism.Antioxidant will be a new strategy for the treatment of uveitis.
出处
《国际眼科纵览》
2013年第4期284-288,共5页
International Review of Ophthalmology
