摘要
目的探讨采用纳洛酮治疗急性颈内动脉系统脑梗死患者的疗效和临床效果，并研究纳洛酮与患者血清超敏C反应蛋白含量的关系。方法对我院2011年7月～2012年12月收治的90例急性颈内动脉系统脑梗死患者进行回顾性研究，根据治疗方法不同分为对照组和观察组，每组各45例，对照组采用一般性常规治疗，观察组在常规治疗的基础上采用纳洛酮进行治疗，观察两组患者在治疗前后功能缺损评分（NDS）和血清超敏C反应蛋白（hs—CRP）等项目的数据变化。结果在对两组患者进行治疗后，NDS和hs—CRP浓度明显降低，观察组患者两项指标下降更明显，差异有统计学意义（P〈0．05）。结论针对急性颈内动脉脑梗死的患者，采用纳洛酮对其联合治疗，能够显著改善患者的病症，减轻其痛苦，还能提高对患者的临床疗效。
Objective To explore the clinical efficacy of naloxone on hs-CRP content of acute cerebral infarction patients with carotid artery system, and to research the relationship of naloxone and hs-CRP content. Methods 90 acute cerebral infarction patients with carotid artery system in our hospital from July 2011 to December 2012 were selected and retrospectively analyzed, the patients were divided into control group and observation group according to different treatments, each had 45 cases, the control group was treated by general treatment, the observation group was treated by general treatment and naloxone, observed NDS and hs-CRP data changes of the two groups before and after the treatment. Results After the treatment, NDS and hs-CRP levels were significantly lower, the indicators of observation group decreased more significantly, there had statistically significant（P 〈 0.05）. Conclusion For acute internal carotid artery in patients with cerebral infarction, naloxone combination therapy can significantly improve the patient＇s symptoms, alleviate their suffering, also can improve the patient＇s clinical efficacy.
出处
《中国医药科学》
2013年第18期83-84,共2页
China Medicine And Pharmacy
关键词
纳洛酮
急性颈内动脉
脑梗死
Naloxone
Acute cerebral carotid artery
Infarction
