摘要
目的探讨声带浅固有层切除术治疗声带白斑的疗效及术后转归特点。方法 2006年1月-2011年12月对138例声带白斑患者分别行声带黏膜剥脱术(剥脱组,69例)和声带浅固有层切除加或不加缝合术(切除组,69例),术前、术后2周、4周、6周、8周、3月、6月、12月行动态喉镜检查和嗓音主客观声学分析,观察两组疗效及术后转归特点。结果术后2周两组的声带黏膜波、声带振动对称性、规律性、总嘶哑度(G)、jitter、shimmer、NHR值均明显低于术前,差异均有统计学意义(P<0.05),但两组间无统计学差异(P>0.05)。剥脱组术后4周动态喉镜、嗓音主客观声学分析均较术后2周明显改善,差异有统计学意义(P<0.05),而与术后6周及之后各时间点比较均无统计学差异(P>0.05)。切除组患者术后6周动态喉镜、嗓音主客观声学分析G、jitter、shimmer、NHR与术后2、4周比较差异均有统计学意义(P<0.05),但与术后8周及以后各时间点比较均无统计学差异(P>0.05)。剥脱组患者嗓音恢复更快,切除组复发率明显低于剥脱组,差异有统计学意义(P<0.05)。结论声带浅固有层切除术治疗声带白斑复发率低,嗓音恢复良好,值得推广。
Objective To study the curative effects and characteristics of vocal cord shallow lamina propria resection on the treatment of vocal cord leukoplakia. Methods A total of cases of vocal cord leukoplakia were received vocal cord mucosa stripping surgery （69 cases） and vocal superficial lamina propria resection with or without suture （69 cases） respectively during January 2006 - December 2011, and all cases were taken dynamic laryngosco- py and voice acoustic analysis before surgery ,at 2 weeks, 4 weeks, 6 weeks, 8 weeks,3 months, 6 months, and 12 months after surgery. We observed the curative effects and characteristics after operation of two different surgery on the treatment of vocal cord leukoplakia with precancerous lesions. Results Two week after operation, the vocal cords mucous wave, vocal cords vibration symmetry, regularity, total hoarseness degree （G）, Jitter, Shimmer, NHR values in the 2 groups were significantly lower than those of preoperation（P^0.05）, but there were no signif- icant differences between the two groups（P^0.05）. The three main index of dynamic laryngoscope , voice acoustic parameters at 4 weeks after operation were significantly lower than those at 2 weeks after operation in the vocal cord mucosa stripping surgery group, the difference were statistically significant （P〈0.05）, but it showed no statistical difference between the group at 6 weeks after operation and the groups at other time points （P〉0.05）. The three main index of dynamic laryngoscope , voice acoustic parameters at 6 weeks after operation were significantly lower than those at 2,4 weeks after operation in the vocal cord shallow lamina propria resection group, the difference were statistically significant （P〈O. 05）, but it showed no statistical difference between the group at 8 weeks after operation and the groups of other time points （P〉0.05）. The voice restoration was faster in the vocal cord mucosa stripping surgery group. The recurrence rate was lower in the vocal cord shallow
出处
《听力学及言语疾病杂志》
CAS
CSCD
北大核心
2013年第5期489-493,共5页
Journal of Audiology and Speech Pathology
关键词
声带白斑
声带浅固有层切除术
声带黏膜剥脱术
Vocal cord leukoplakia
Vocal cord shallow lamina propria resection
Vocal cord mucosa stripping surgery
