摘要
目的研究缺血性脑卒中患者血清尿酸水平与颅内动脉狭窄的关系。方法对60例缺血性脑卒中患者进行数字减影血管造影检查，根据其颅内动脉狭窄程度分为狭窄组与无狭窄组。检测其血清尿酸、血脂及同型半胱氨酸（Hey）水平，并进行比较。结果根据DSA检查结果，将患者分为狭窄组（45例）和无狭窄组（15例）。狭窄组男性、高血压、糖尿病、吸烟史、饮酒史、高血脂的比率及血尿酸水平显著高于无狭窄组（P〈0．05～0．01）。Logistic回归分析显示，高血压是颅内动脉狭窄的独立危险因素（OR=55．730，95％CI：1．100—2823．152；P〈0．05）。结论高尿酸与颅内动脉狭窄有关，但不是其独立危险因素。
Objective To study the relationship between the level of serum uric acid and intracranial stenosis in patients with cerebral ischemic stroke. Methods Sixty cerebral isehemic stroke patients were checked by digital subtraction angiography （DSA）. According to the degree of intracranial stenosis, patients were divided into stenosis group and no stenosis group. The levels of serum uric acid, blood fat, homocysteic acid （Hcy） in the two groups were detected, and the results were compared. Results According to the result of DSA, patients were divided into stenosis group （45 cases） and no stenosis group （15 cases）. The rates of male, hypertension, diabetes, smoking, drinking, hyperlipidemia and the level of serum uric acid in stenosis group were significantly higher than those in no stenosis group （ P 〈 0. 05 - 0. 01 ）. Logistic regression analysis showed hypertension was the independent risk of intracranial stenosis （ OR = 55. 730,95% CI：I. 100 -2823. 152 ;P 〈 0. 05）. Conclusion High uric acid is related to i ntracranial stenosis, but it is not the independent risk of intracranial stenosis.
出处
《临床神经病学杂志》
CAS
北大核心
2013年第4期301-303,共3页
Journal of Clinical Neurology
关键词
尿酸
颅内动脉狭窄
缺血性脑卒中
uric acid
intracranial stenosis
cerebral ischemic stroke
