摘要
目的:探讨透明质酸钠对剖宫产产妇血清基质金属蛋白酶9(MMP-9)、一氧化氮(NO)、层粘蛋白(LN)及炎性因子的影响。方法:选取2010年11月-2012年10月于该院进行常规处理的45例剖宫产产妇为对照组,并将同一时期采用透明质酸钠处理的45例产妇选为观察组,然后将两组产妇产前与产后不同时间的血清MMP-9、NO、LN及炎性因子水平进行比较。结果:观察组产后不同时间的血清MMP-9高于对照组,NO、LN及炎性因子水平低于对照组,P值均<0.05,均有统计学差异。结论:透明质酸钠对剖宫产产妇血清MMP-9、NO、LN及炎性因子的影响较为明显,对于控制粘连及感染的发生均有积极的临床作用。
Objective： To investigate the effect of sodium hyaluronate on the serum MMP -9, NO, LN and inflammatory factors of puerperants with cesarean section. Methods： 45 puerperants with cesarean section and treated with normal method November 2010 to Oc- tober 2012 were collected into control group, 45 cases treated with sodium hyaluronate were selected into observation group, then the serum MMP- 9, NO, LN and inflammatory factors of two groups before the delivery and at different times after the delivery were compared. Results ： Serum MMP - 9 of observation group at different times after the delivery were all higher than those of control group, NO, LN and inflammatory factors were all lower than those of control group, allP 〈 0. 05, there were all significant differences. Conclusion ： Effect of sodium hyaluronate on serum MMP - 9, NO, LN and inflammatory factors of puerperants with cesarean section is obvious, and it plays active clinical role in controlling the adhesion and infection.
出处
《中国妇幼保健》
CAS
北大核心
2013年第26期4397-4399,共3页
Maternal and Child Health Care of China
关键词
透明质酸钠
剖宫产产妇MMP-9
NO
LN炎性因子影响
Sodium hyaluronate
Puerperants with cesarean section
MMP-9
NO
LN
Inflammatory fac-tors
Effect
