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冻融周期与新鲜周期囊胚移植的临床结局分析 被引量:12

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摘要 目的 比较冻融周期和新鲜周期囊胚移植的临床妊娠结局。方法 回顾性分析2010年1月至2011年12月期间,在第四军医大学第二附属医院生殖医学中心行囊胚移植的385例患者的妊娠情况,其中,115个周期为冻融周期囊胚移植,270个周期为新鲜周期囊胚移植。结果 冻融周期行囊胚移植,临床妊娠率(CPR)显著高于新鲜周期(69.56%vs.53.7%)(P<0.05);冻融周期中,冻融囊胚的种植率(IR)显著高于新鲜周期组(47.26%vs.36.98%,P<0.05);出生率:截止到2012年4月,冻融周期和新鲜周期具有相似的出生率,然而,冻融周期的多胎妊娠率(MPR)显著高于新鲜周期组(43.75%vs.25.52%,P<0.05);冻融周期和新鲜周期中均移植2个囊胚时,冻融周期的CPR和IR(75.4%,58.5%)均高于新鲜周期组(57.1%,37.1%),且差异有统计学意义(P<0.05)。结论 冻融周期进行囊胚移植不仅不会降低CPR和出生率,而且可以提高IR,因此冻融周期减少移植囊胚数目,可以达到降低MPR的风险,进而获得更为理想的临床结局。
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2013年第8期671-674,共4页 Chinese Journal of Practical Gynecology and Obstetrics
关键词 新鲜周期 冻融周期 囊胚 多胎妊娠 fresh cycle frozen-thawed blastocyst multiplets pregnancy
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参考文献12

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