摘要
目的比较末次月经推算法（LMP法）和B超双顶径计算法（BPD法）估算孕龄的差异，探讨两种方法估算孕龄对唐氏筛查结果的影响。方法选取2010年12月～2011年10月在本院进行唐氏筛查和胎儿B超双顶径检查的全部孕妇作为研究对象，共242人，以B超检查时间为基准，用两种方法估算孕龄并进行回归分析；以唐氏筛查抽血时间为基准，分别用两种方法估算的孕龄进行唐氏风险值计算，比较两种方法高风险率差异。结果两种方法回归公式为Y=-0．801x＋14．245，R2=0．1047。在17．77W之前，LMP法推算孕龄有大于BPD法的趋势；17．77W后，LMP法推算孕龄有小于BPD法的趋势；随孕龄增加，BPD法离散度增大。BPD法唐氏筛查高风险率高于LMP法。结论BPD法随孕龄增加误差增大，现用的BPD法计算孕龄的公式已不适合国情，急需根据我国人群建立BPD计算孕龄的公式。
Objective To make comparison of difference in estimating gestational age between the methods of last menstrual period （LMP） and ultrasonic biparietal diameter （BPD）, and to discuss the effects of those two method on the screening results of Down syndrome. Methods 242 pregnant women, who received Down syndrome screening and ultrasonic biparietal diameter between December 2010 and October 2011 ,were selected as subjects. Taking the ultrasound examination time as the standard, the methods above were used to estimate the gestational age, and regression analysis was made. Using the hemospasic time of Down syndrome screening as the standard, the gestational age estimated by the two methods above was used to calculate the risk value of Down syndrome. Comparison was made in the difference of high risk rate between the two methods. Results The regression formulae of the two methods were y = -0. 801x ＋ 14. 245 ,R2 =0. 1047. Before 17.77 w,there was a tendency that the gestational age estimated by LMP method was larger than that estimated by BPD method. After 17.77 w, there was a tendency that the gestational age estimated by LMP was smaller than that estimated by BPD. Along with the increase of gestational age, the discrete degree of BPD increased. The BPD high risk rate of Down syndrome screening was higher than LMP. Conclusion Along with the increase of gestational age, the error of BPD increases. The present BPD estimating formula of gestational age is not suitable for our national condition. New BPD estimating formula of gestational age should be established according to our country. population.
出处
《西南国防医药》
CAS
2013年第8期869-871,共3页
Medical Journal of National Defending Forces in Southwest China
关键词
孕龄
双顶径
末次月经
推算法
唐氏综合征
gestational age
biparietal diameter
last menstrual period
estimation
Down syndrome
