摘要
目的:探讨比较经尿道前列腺电切术和口服药物治疗良性前列腺增生合并2型糖尿病患者的有效性和安全性。方法:86例良性前列腺增生合并2型糖尿病患者,随机分成经尿道前列腺电切手术组(A组,n=46)和口服药物组(B组,n=40)。分别观察两组治疗1年后疗效与并发症,分别测定1年前后各患者最大尿流率(Qmax)、膀胱残余尿量(postvoid residualurine volume,PRV)及国际前列腺症状评分(International Prostate Symptom Score,IPSS)、生活质量评分(Quality of life score,QOL)。结果:两组患者年龄及治疗前Qmax、PRV、IPSS、QOL比较均无统计学差异(P>0.05)。1年后两组比较,A组疗效及并发症,最大尿流率、IPSS及QOL明显优于B组,差异有统计学意义(P<0.01);但两组膀胱残余尿量差异无统计学意义(P>0.05)。结论:经尿道前列腺电切术较口服药物能够明显改善患者膀胱梗阻,降低尿路感染及尿潴留风险,延缓膀胱收缩功能障碍。
Objective：To evaluate and compare the efficacy and safety between transurethral resection of the prostate （TURP） and o- ral drugs treatment for benign prostatic hyperplasia（BPH） with type 2 diabetes mellitus （T2DM）. Methods： 86 patients with BPH and coexisting T2DM were randomly divided into TURP group （group A, n = 44） and oral drugs group （group B, n = 40）. The cura- tive effects and complications of the patients in two groups were observed for 1 year, and figures before and after 1 year of Qmax, PRV and IPSS, QOL were measured. Results ： There is no statistical difference of age and preoperative Qmax, PRV, IPSS, QOL figures in the two groups （P 〉0.05）. One year later, The curative effects and complications of Qmax, IPSS and QOL in group A were signifi- cantly better than group B, and the differences were statistically significant （P 〈 0.01 ） ; But there is no statistical significance of PRV differences in the two groups （P 〉 0.05）. Conclusion ： Compared with oral drugs treatment, the TURP can apparently reduce bladder outlet obstruction, lower urinary tract infections and urinary retention risk of patients with BPH and DM, and it has more apparent effect in delaying bladder systolic dysfunction.
出处
《川北医学院学报》
CAS
2013年第4期381-384,共4页
Journal of North Sichuan Medical College
关键词
良性前列腺增生
2型糖尿病
经尿道前列腺电切术
口服药物
Benign prostatic hyperplasia （ BPH ）
Type 2 diabetes mellitus （ T2DM ）
Transurethral resection of prostate （TURP）
Oral drugs
