摘要
目的评价听觉诱发电位指数（AAI）监测幼儿吸人七氟醚麻醉深度的准确性。方法择期全麻手术患儿50例，年龄1～3岁，ASA分级Ⅰ或Ⅱ级，异丙酚-顺阿曲库铵-瑞芬太尼麻醉诱导气管插管后行机械通气，维持PETCO2 35-45mmHg。随后高氧流量6L／min洗入七氟醚，15min后氧流量降低为3L／min，调节呼气末七氟醚浓度（C_ET Sev）依次为2．5％、2．8％、3．0％、3．5％、3．7％、4．0％，每个C_ET Sev维持稳态3min。分别于麻醉诱导前、诱导后、吸人七氟醚前即刻和不同C_ET Sev稳态时监测AAI。结果AAI与C_ET Sev呈明显负相关（r=-0．872，P〈0．01）。结论单纯吸人七氟醚1．0～1．6MAC时AAI可准确监测幼儿的麻醉深度。
Objective To evaluate the accuracy of auditory evoked potential index （AAI） in monitoring the depth of sevoflurane anesthesia in infants. Methods Fifty ASA Ⅰ or Ⅱ pediatric patients, aged 1-3 yr, scheduled for elective surgery under general anesthesia, were enrolled in this study. Anesthesia was induced with propofol, cisatracurium and remifentanil. The patients were tracheal intubated and mechanically ventilated. PET CO2 was maintained at 35-45 mm Hg. Anesthesia was maintained with inhalation of sevoflurane. Fresh gas flow was first set at 6 L/min for 15 min and then reduced to 3 L/min. The end-tidal sevoflurane concentration （CETSeV） was maintained at 2.5% , 2.8% , 3.0% , 3.5% , 3.7% and 4.0% . Each C_ET SeV was maintained for 3 min. AAI was continuously monitored before induction of anesthesia, after induction, immediately before sevoflurane in- halation, and at the 6 CET Sev. Results AAI was negatively correlated with CET Sev （ r = - 0. 872, P 〈 0.01 ） . Conclusion AAI can accurately reflect the depth of sevoflurane anesthesia in infants.
出处
《中华麻醉学杂志》
CAS
CSCD
北大核心
2013年第4期470-472,共3页
Chinese Journal of Anesthesiology
基金
泉州市第二批技术研究与开发项目（2011238）
关键词
诱发电位
听觉
监测
手术中
儿童
麻醉药
吸入
Evoked potentials, auditory
Monitoring, intraoperative
Child
Anesthetics, inhalation
