摘要
目的探讨血清同型半光氨酸(Hcy)的检测在心血管疾病中的临床价值。方法选取该院心内科收治的99例冠心病(CHD)患者进行Hcy检测,另抽取同期在本院保健科进行健康体查的健康人群86例作为对照组。结果 CHD组患者的血清Hcy水平明显比对照组升高,差异有统计学意义(P<0.05),99例CHD患者中有59例检出Hcy阳性,占59.59%,而对照组中只有3例检出Hcy阳性,占3.48%,CHD患者组中检出Hcy阳性率明显比对照组高(P<0.05)。对各类型CHD组的检测结果进行比较,本研究发现陈旧性心肌梗死组的Hcy水平、Hcy阳性率比不稳定型心绞痛组明显升高(P<0.05),不稳定型心绞痛组的Hcy水平、Hcy阳性率比稳定型心绞痛组明显升高(P<0.05)。结论 Hcy是心血管疾病中的一个独立危险因子,其水平随着CHD病程的加重而升高,因此,血清Hcy的检测在心血管疾病诊断和治疗中有着重要的临床价值。
Objective To discuss the clinical value of homoHcysteine（Hcy） detection on cardiovascular diseases. Methods 99 cases of coronary heart disease（CHD）from department of cardiologic medicine in our hospital were collected as CHD group, and the level of Hcy was tested,86 cases of healthy people from health care department in our hospital were as control group. Results The level of Hcy in CHD group was higher than that in control one,and the difference was significant（P〈0.05）. 59 out of 99 cases in cHD group were detected of Hcy, accounted for 59.59%, and only 3 cases in control group were detected of Hcy, accounted for 3.48%, the positive detection rate of Hcy in CHD group was higher than that in control one（P〈0.05）. In CHD group, the level and positive rate of Hcy in old myocardial infarction patients were higher than that in unstable angina pectoris patients（P〈0.05）, and the level and positive rate of Hcy in unstable angina pectoris patients were higher than that instable angina pectoris patients（P 〈0.05）. Conclusion Hcy is an independent risk factor in cardiovascular diseases,and its level increases with aggravation of CHD, so detection on serum level of Hcy has the important clinical value on diagnosis and treatment of cardiovascular diseases.
出处
《重庆医学》
CAS
CSCD
北大核心
2013年第16期1833-1834,共2页
Chongqing medicine
