摘要
目的 探讨血清(浆)同型半胱氨酸在肝病时的临床应用价值。方法 根据临床诊断或金标准确诊的慢性肝病、肝硬化及原发性肝癌病例血清(浆)同型半胱氨酸浓度改变情况,评价其灵敏度和特异性,与常规检测慢性肝病项目的灵敏度和特异性进行比较。结果 显示血清(浆)同型半胱氨酸检测对于慢性肝病、肝硬化和肝癌诊断的灵敏度和特异性均高于常规方法。结论 由于有较高的灵敏度和特异性,且检测方便、费用较低,可作为临床慢性肝病的检测和大范围的慢性肝病筛选普查的一个重要指标。
Objective To study the clinical used value of the serum (plasma) homocysteine in the diagnosis of chronic hepatic disease Methods To evaluate the sensibility and specificity of the assay through the concentration change of the serum(plasma) homocysteine in the chronic hepatic disease, cirrhosis and primary liver cancer which were diagnosed by clinical and golden standard. To compave it with the routine laboratory tests. Results Both the sensibility and specificity of diagnosing chronic hepatic disease with serum (plasma) homocysteine concentration was higher than the routine laboratory tests. Conclusions The assay can be used in the monitoring of the chronic hepatic disease and large - scale screening based on its high sensibility and specificity, easy operation and lower expenditure.
出处
《全科医学临床与教育》
2003年第2期16-18,共3页
Clinical Education of General Practice
