摘要
目的观察卡络磺钠和氨甲环酸在治疗肺结核咯血方面的临床效果。方法将2010年1月～2012年6月期间收治的60例肺结核咯血患者为研究对象,将其随机分为两组,A组(n=30)患者采用卡络磺钠治疗,B组(n=30)采用氨甲环酸治疗,对比分析两组患者的临床效果以及不良反应。结果 A组的止血时间(5.6±3.0)h要略短于B组的止血时间(6.0±3.3)h,但两组止血时间差异不显著,不具有统计学意义(P>0.05);经过治疗后,A组总有效率为93.5%,B组总有效率为90.0%,两组差异不显著,不具有统计学意义(P>0.05);A组未出现不良反应,B组有7例患者出现不良反应,两组差异显著,具有统计学意义(P<0.05)。结论对于轻度肺结核咯血而言,建议采用卡络磺钠进行治疗,对于较为严重的肺结核咯血而言,建议首选氨甲环酸进行治疗。
Objective Observation of carbazochrome sodium sulfonate and tranexamic acid in the treatment of hemoptysis of pulmonary tubemulosis the clinical effect. Methods In 2010 January2012 June treated 60 cases of patients with pulmonary tuberculosis hemoptysis as the research object, divide them into two groups, Group A （n=30） patients using carbazochrorne sodium sulfonate treatment, B group （n=30） using tranexamic acid treatment, comparative analysis of two groups of patients with clinical effects and adverse reactions. Results A group （5.6_＋ 3） bleeding time is slighUy shorter than the H B group （6_＋3.3） bleeding time of H, but the two groups of hemostatic time difference was not significant, the difference was not statistically significant （P〉0.05）; after treatment, A group total effective rate was 93.5% total effective rate was 90% in group B the two group, no significant difference, the difference was not statistically significant （P〉0.05）; A group did not show any adverse reaction in 7 cases in group B, the occurrence of adverse reactions, between the two groups was significant, with statistical significance （P〈0.05）. Conclusion For mild hemoptysis of pulmonary tuberculosis, recommended the use of carbazochrome sodium sulfonate treatment, for the more serious hemoptysis of pulmonary tuberculosis, suggested that the preferred tranexamic acid treatment.
出处
《中国药物经济学》
2013年第2期76-77,共2页
China Journal of Pharmaceutical Economics
关键词
卡络磺钠
氨甲环酸
肺结核咯血
疗效对比
Carbazochrome sodium sulfonate
Tranexamic acid
Tuberculosis hemoptysis
Comparative efficacy
