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泮托拉唑联合卡络磺钠治疗上消化道出血临床观察 被引量:7

Effects of pantoprazole combined carbazochrome sodium sulfonate in treatment of upper gastrointestinal bleeding
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摘要 目的探讨泮托拉唑与卡络磺钠联合用于治疗上消化道出血的临床疗效。方法上消化道出血患者122例随机分为观察组与对照组,各61例。除常规对症支持治疗外,观察组加用泮托拉唑与卡络磺钠联合治疗,对照组加用泮托拉唑治疗,对比2组临床效果。结果观察组显效率和总有效率为68.85%(42/61)和95.08%(58/61),对照组分别为39.34%(24/61)、81.97%(50/61),差异有统计学意义(P〈0.05);观察组出血时间与输血量低于对照组,治疗后胃液pH值与血红蛋白水平高于对照组,差异有统计学意义(P〈0.05或P〈0.01)。结论泮托拉唑与卡络磺钠联合用于治疗上消化道出血能够高效、快速地控制出血,提高临床疗效。 Objective To evaluate the pantoprazole ate in treatment of upper gastrointestinal bleeding. Methods combined carbazochrome sodium sulfon- A total of 122 patients with upper gas- trointestinal bleeding were randomly divided into study group ( n = 61 ) and the control group ( n = 61 ). Both groups received routine and supportive treatment. Observation group received combined adminis- tration of pantoprazole with carbazochrome sodium sulfonate, while the control group received panto- prazole. Results The effective rate and total efficacy rate were 68.85% and 95.08% in study group and were 39.34% and 81.97% in control group (P 〈0.05). Study group had shorter bleeding time, less blood transfusion volume, higher gastric pH value and hemoglobin level compared with the control group after treatment (P 〈 0. 05, P 〈 0. 01 ). Conclusion pantoprazole combined carbazochrome so- dium sulfonate iseffective in treatment of upper gastrointestinal bleeding
作者 李国波
出处 《实用临床医药杂志》 CAS 2015年第E01期105-106,116,共3页 Journal of Clinical Medicine in Practice
关键词 上消化道出血 泮托拉唑 卡络磺钠 upper gastrointestinal bleeding pantoprazole carbazochrome sodium sulfonate
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