摘要
目的探讨乙肝后肝硬化中医证型与肝功能CTP（Child-Turcotte-Pugh）分级、终末期肝病模型（modelforend-stageliverdisease，MELD）评分的相关性。方法一对符合乙肝后肝硬化标准的135例患者进行规范中医辨证、实验室检查，并对其肝功能CTP分级、MELD评分与中医证型相关性进行分析。结果乙肝后肝硬化肝功能CTP分级、MELD评分与中医辨证分型具有一定的相关性，伴随病情进展，证型分布呈动态变化，肝气郁结、湿热蕴结是乙肝后肝硬化病情轻、中度阶段的主要证型，肝功能CTP分级以A级为主，MELD评分以小于10分为主；肝肾阴虚、脾肾阳虚、瘀血阻络三型是病情严重阶段的主要证型，肝功能CTP分级多为B、C级，MELD评分多在10分以上。结论与中医关于肝硬化病机演变气滞、湿热-水停、血瘀-阳虚、阴虚的传统认识相符合。
Objective To explore and identify the correlation of CTP classification, MELD score of patients with cirrhosis after hepatitis between different TCM syndromes. Methods For 135 patients comply with hepatitis B cirrhosis standard, standardized TCM syndrome differentiation and laboratory tests is executed so as to analyze the correlation of CTP classification, MELD score of patients with cirrhosis after hepatitis between different TCM syndromes. Results The liver function CTP classification in liver Qi stagnation syndrome and dump-heat accumulation syndrome patients mainly scores to Class A, and the MELD score less than 10 points-based. The liver function CTP classification in Yin deficiency of Liver and kidney, Yang deficiency of spleen and kidney and blood stasis syndromes mainly scores to Class B-C, and the MELD scores more than 10 points basically. Yin deficiency of Liver and kidney, Yang deficiency of spleen and kidney and blood stasis syndromes take majority in advanced cirrhosis patients compared with liver Qi stagnation syndrome and dump-heat accumulation syndrome take majority in early stage cirrhosis patients. Conclusion Matches the traditional view in TCM that form Qi stagnation, to damp heat-water stopped, to blood stasis-Yang and Yin deficiency is the regular pathogenesis evolution pattern of post-hepatitis cirrhosis.
出处
《国际中医中药杂志》
2013年第4期292-294,共3页
International Journal of Traditional Chinese Medicine
