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局部0.25%布比卡因用药时间对腹腔镜胆囊切除术后切口疼痛的影响 被引量:2

Effects of bupivacaine infiltration on postoperative pain after laparoscopic cholecystectomy
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摘要 目的探讨腹腔镜胆囊切除术(LC)中4个切口局部浸润0.25%布比卡因时间对术后切口疼痛的影响。方法采用随机数字表法将75例LC患者分为A、B和对照组,各25例。A组在麻醉后切皮前以3ml 0.25%布比卡因分别对4个切口(分别为剑突下、右腋前线肋缘下、右锁骨中线肋缘下以及脐孔)进行全层浸润;B组在手术结束后患者清醒前进行局部浸润;对照组不予局部浸润。术后均不给予镇痛药。采用视觉模拟评分(VAS)评价镇痛效果。结果术后1、2、4、6、8h,B组剑突下切口的静态VAS[分别为(1.9±1.7)、(1.6±1.4)、(1.2±1.1)、(0.8±0.7)、(0.6±0.5)分]明显低于对照组[分别为(4.6±1.9)、(3.8±2.1)、(2.6±1.7)、(2.1±1.5)、(1.5±1.3)分](均P〈0.05);术后1、2、4、6、8、24h,B组动态VAS[分别为(2.7±2.4)、(2.4±2.2)、(1.8±1.6)、(1.5±1.3)、(1.1±1.0)、(0.9±0.8)分]明显低于对照组[分别为(5.7±2.4)、(5.0±2.6)、(3.5±1.9)、(2.9±1.9)、(2.4±2.3)、(2.3±2.2)分](均P〈0.05)。结论LC患者清醒前给予0.25%布比卡因局部浸润可以明显减轻剑突下切口术后疼痛。 Objective To investigate the effect of 0.25 % bupivaeaine infiltration of troear sites at different times on postoperative pain after laparoseopie eholeeysteetomy(LC). Methods Seventy-five patients scheduled for selective LC were randomized into three groups with 25 eases each. The four troear sites were infiltrated with 3 ml of 0.25% bupivacaine just before the operation(group A)or just at the end of the operation (group B). Group C was not given bupivaeaine infiltration as the control. Postoperative pain visual analogue scale (VAS)was recorded at rest and during movement. No patients were administered analgetiea. Results For the subxiphoid incision, VAS at rest in group B [ 1 h( 1.9 ± 1.7) scores, 2 h( 1.6 ± 1.4) scores, 4 h ( 1.2 ± 1.1 ) scores, 6 h (0.8 ± 0.7) scores, 8 h (0.6 ± 0.5 ) scores ] were siguifieantly lower than those in group C [ 1 h (4.6 ± 1.9 ) scores, 2 h ( 3.8 ± 2.1 ) scores, 4 h(2.6 ± 1.7) scores, 6 h(2.1 ± 1.5 ) scores, 8 h ( 1.5 ± 1.3 ) scores ] after the operation ( P 〈 0.05 ). While VAS during movement in group B [ 1 h(2. 7 ± 2.4) scores, 2 h (2.4 ± 2.2 ) scores, 4 h ( 1.8 ± 1.6) scores, 6 h ( 1.5 ± 1.2 ) scores, 8 h ( 1.1 ± 1.0 ) scores, 24 h ( 0.9 ± 0.8 ) scores ] were siguifieantly lower than those in group C [ 1 h (5.7 ± 2.4) scores, 2 h (5.0 ± 2.6) scores, 4 h (3.5 ± 1.9) scores, 6 h (2. 9 ± 1.1 ) scores, 8 h(2.4 ± 2.3 ) scores, 24 h(2.3 ±2.2) scores] after the operation(P 〈0.05). Conclusion The infiltration of 0. 25% bupivaeaine just at the end of operation at the subxiphoid incision can effectively decrease the postoperative ineisional pain.
出处 《中国医药》 2013年第4期533-534,共2页 China Medicine
关键词 胆囊切除术 腹腔镜 疼痛 手术后 局部浸润 布比卡因 Choleeysteetomy, laparoseopie Pain, postoperative Local infiltration Bupivaeaine
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  • 1佘守章.新型阿片类药物在病人自控镇痛中应用研究的进展[J].临床麻醉学杂志,2006,22(11):874-877. 被引量:23
  • 2王庚,吴新民.瑞芬太尼复合麻醉患者术后急性阿片类药物耐受的发生[J].中华麻醉学杂志,2007,27(5):389-392. 被引量:88
  • 3严相默 主编.临床疼痛学.第2版[M].延边:延边人民出版社,1996.56-64. 被引量:1
  • 4Woolf CJ.Generation of acute pain:central mechanisms.Br Med Bull 1991; 47:523-533 被引量:1
  • 5Lohsiriwat V,Lert-akyamanee N,Rushatamukayanunt W.Efficacy of pre-incisional bupivacaine infiltration on postoperative pain relief after appendectomy:prospective double-blind randomized trial.World J Surg 2004; 28:947-950 被引量:1
  • 6Gottschalk A,Smith DS.New concepts in acute pain therapy:preemptive analgesia.Am Fam Physician 2001; 63:1979-1984 被引量:1
  • 7Reuben SS.Update on the role of nonsteroidal antiinflammatory drugs and coxibs in the management of acute pain.Curr Opin Anaesthesiol 2007; 20:440-450 被引量:1
  • 8Reuben SS,Buvenandran A,Katz B,Kroin JS.A prospective randomized trial on the role of perioperative celecoxib administration for total knee arthroplasty:improving clinical outcomes.Anesth Analg 2008; 106:1258-1264,table of contents 被引量:1
  • 9Tiippana E,Bachmann M,Kalso E,Pere P.Effect of paracetamol and coxib with or without dexamethasone after laparoscopic cholecystectomy.Acta Anaesthesiol Scand 2008;52:673-680 被引量:1
  • 10Papadima A,Lagoudianakis EE,Antonakis PT,Pattas M,Kremastinou F,Katergiannakis V,Manouras A,Georgiou L.Parecoxib vs.lornoxicam in the treatment of postoperative pain after laparoscopic cholecystectomy:a prospective randomized placebo-controlled trial.Eur J Anaesthesiol 2007;24:154-158 被引量:1

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