摘要
目的:分析丙泊酚与瑞芬太尼复合罗哌卡因局部浸润对腹腔镜胆囊切除术(LC)患者麻醉效果的影响。方法:选择2022年1月—2024年1月宜宾市第三中医医院收治的120例LC患者作为研究对象;以随机数表法将其分为参照组和试验组,各60例。参照组以丙泊酚复合芬太尼作为麻醉方案,试验组以丙泊酚与瑞芬太尼复合罗哌卡因作为麻醉方案。观察两组间麻醉恢复效果、认知功能及麻醉安全性效能差异。结果:试验组苏醒时间、意识恢复时间及拔管时间均早于参照组,术后疼痛开始时间晚于参照组,差异有统计学意义(P<0.05)。术前,两组简易精神状态检查表(MMSE)评分比较,差异无统计学意义(P>0.05);拔管后1 h、6 h、24 h,试验组MMSE评分均高于参照组,差异有统计学意义(P<0.05)。试验组不良反应总发生率明显低于参照组,差异有统计学意义(P<0.05)。结论:LC患者采用丙泊酚与瑞芬太尼复合罗哌卡因局部浸润麻醉后恢复效果更好,可促进患者术后认知功能恢复方面,保障麻醉安全性。
Objective:To analyze the effect of local infiltration of Propofol and Remifentanil combined with Ropivacaine on anesthesia in patients undergoing laparoscopic cholecystectomy(LC).Method:A total of 120 patients with LC treated in Yibin Third Traditional Chinese Medicine Hospital from January 2022 to January 2024 were selected as the study objects.Random number table method was used to divide the patients into the reference group and the experimental group,with 60 cases in each group.The reference group was treated with Propofol combined with Fentanyl,and the experimental group was treated with Propofol and Remifentanil combined with Ropivacaine.The effects of recovery,cognitive function and safety of anesthesia between the two groups were observed.Result:The recovery time,consciousness recovery time and extubation time of experimental group were earlier than those of reference group,and the onset time of postoperative pain was later than that of reference group,the differences were statistically significant(P<0.05).Before operation,there was no significant difference in mini-mental state examination(MMSE)scores between the two groups(P>0.05).At 1 h,6 h and 24 h after extubation,MMSE scores of experimental groups were higher than those of reference group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in experimental group was significantly lower than that in reference group,and the difference was statistically significant(P<0.05).Conclusion:Patients undergoing LC with Propofol and Remifentanil combined with Ropivacaine has better recovery effect after local infiltration anesthesia,which can promote postoperative cognitive function recovery of patients and ensure the safety of anesthesia.
作者
代明镜
DAI Mingjing(Yibin Third Traditional Chinese Medicine Hospital,Yibin 644600,China)
出处
《中外医学研究》
2024年第17期114-117,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
丙泊酚
瑞芬太尼
腹腔镜胆囊切除术
麻醉效果
认知功能
麻醉安全性
Propofol
Remifentanil
Laparoscopic cholecystectomy
Anesthesia effect
Cognitive function
Safety of anesthesia
