摘要
目的评价检测降钙素原(PCT)与C反应蛋白(CRP)水平对成人下呼吸道感染诊断的临床意义。方法52例细菌感染下呼吸道感染患者血清PCT、CRP的含量及动态变化进行检测,按不同感染类型分类比较降钙素原水平的差异。结果细菌感染组(8.9±1.2)ng/mL,非细菌感染组(0.1±0.09)ng/mL,两组比较差异有统计学意义(P<0.05)。细菌感染不同类型感染组降钙素原比较:脓毒症组、医院获得性感染组、慢性阻塞性肺疾病急性加重组与非细菌感染组比较,差异有统计学意义(P<0.05),其他下呼吸道感染组与非细菌组比较差异无统计学意义(P>0.05)。对细菌培养阳性病例进行APACHE评分存在正相关性(r=0.58,P=0.02)。结论血清PCT、CRP联合检测在细菌感染的早期诊断中有一定价值,动态监测PCT水平有助于评估治疗效果。
Objective To evaluate the clinical value of procalcitonin （PCT） and C-reactive protein （CRP） on the di- agnosis of adult respiratory infections. Methods A total of 52 cases of bacterial infections of lower respiratory tract in- fections was detdected PCT, CRP corroding to classification according to the different types of infection, and to com- pare with infection group. Results of bacterial infection group （8.9＋l.2）ng/mL, non-bacterial infection group （0.1 _＋ 0.09） ng/mL, the difference was statistically significant （H = 18.12, P = 0.012）. Bacterial infection subgroup analysis of different types of infection sepsis group, hospital-acquired infection group, the reorganization of acute exacerba- tions of chronic obstructive pulmonary disease and non-bacterial infection group, the difference was statistically sig- nificant （P 〈 0.05）, other lower respiratory tract infection group was not statistically significant （P 〉 0.05） compared with non-bacterial. APACHE score and the procaldtonin levels suggesting that there is a positive correlation （r = 0.58, P = 0.02）. Conclusion Serum PCT and CRP joint detection in the early diagnosis of bacterial infections had a useful index to evaluate the lower respiratory infection.
出处
《中国现代医生》
2013年第7期88-89,共2页
China Modern Doctor
关键词
降钙素原
C反应蛋白
细菌感染
Procalcitonin
C-reactive protein
Bacterial infection
