摘要
采用武汉市职工医学院从湖北绿茶中提取的绿茶素 (TP-91 )及湖北大学生命科学院从蚕蛹中提取的壳多糖进行抗肿瘤实验研究。瘤株为小鼠 EAC。结果表明绿茶素及壳多糖对肿瘤的抑瘤率分别为 40 .3 3 %和 5 2 .1 0 % ;对外周血淋巴细胞计数分别为 8.80± 2 .41 ,8.3 0± 3 .1 8与对照组 (2 .84± 0 .61 )比较有显著差异 (P<0 .0 1 ) ;对外周血 T淋巴细胞计数分别为 2 4.2 0± 4.5 6,1 4.1 4± 4.3 7与对照组 (4.1 0± 3 .3 5 )比较有显著性差异 (P<0 .0 1 )。结果提示绿茶素及壳多糖均有抗肿瘤作用 ,显示这两种天然物质在对肿瘤防治方面有良好的发展前景。
We have conducted the experimental research on antineoplastic effect of tea pigment (TP 91) extracted from Hubei green tea by our college and chitin extracted from silkwormchrysalis by Life Science College of Hubei University. Mice EAC were used as experimental subjects. The results showed that the rates of inhibiting tumor of TP 91 and chitin were 40.33% and 52.1% respectively; Lymphocyte counts of peripheral blood were 8.80±2.41 and 8.30±3.18 respectively, which had a significant difference from control group (2.84±0.61), (P<0.01); T lymphocytes counts of peripheral blood were 24.20±4.56 and 14.41±4.37, which were significantly different from control group (4.10±3.35), (P<0.01). The results suggest that both TP 91 and chitin have antineoplastic effect and there will be a good development in preventing and treating tumors.
出处
《时珍国医国药》
CAS
CSCD
2000年第9期783-784,共2页
Lishizhen Medicine and Materia Medica Research
关键词
绿茶素
壳多糖
荷瘤小鼠
抗肿瘤
中药
药理
TP 91
Chitin (poly N acetylglucosamine)
Mice EAC
Antineoplastic
