摘要
目的 研究局部矫形治疗是否对全身机体代谢产生影响。方法 给大鼠下颌戴向后上牵引的矫形器 ,用放射免疫法测定不同加力组大鼠血中环磷腺苷 (cAMP)含量 ,绘制时间 浓度曲线 ,并进行时间生物学的余弦统计分析。结果 对照组大鼠血中cAMP含量存在昼夜节律 ,白天加力组和夜晚加力组大鼠血中cAMP昼夜节律均未消失 ;组间各参数比较的结果较为复杂。结论 局部矫形力可能会影响大鼠机体代谢 ,但需进一步深入研究 ;进行矫形治疗时 ,即要注意局部的治疗作用 ,加力时间的选择 。
Objective To document the effect of orthopedic therapy on the metabolism of rats. Methods Exerting backwards force on rats mandible and measuring concentration of rats' blood cAMP in three groups with radio immunity. Drawing the time concentration curve and making cosine analysis. Results In natural state, there was a diel rhythm change of concentration of cAMP in rats' blood( P <0.05); After being imposed orthopedic forces to inhibit mandibular growth, the normal diel rhythm of cAMP in blood still existed( P <0.05). The results of parameter comparison among groups were more complicated. Conclusion Further research is needed to clarify the mechanism whether local orthopedic forces influence the body metabolism.
出处
《上海口腔医学》
CAS
CSCD
2000年第3期150-152,共3页
Shanghai Journal of Stomatology
基金
国家自然科学基金!(39370746)
