摘要
为了探讨中草药黔岭藿在加速矫治牙齿槽骨改建过程中与环磷酸腺苷（ｃＡＭＰ）的关系，采用放射免疫方法检测了黔岭藿注射液作用的鼠矫治牙齿槽骨内源性ｃＡＭＰ的含量。结果表明，黔岭藿对鼠矫治牙齿槽骨内源性ｃＡＭＰ的含量无明显影响。由此分析，内源性ｃＡＭＰ可能并不参与黔岭藿促进矫治牙齿槽骨组织改建的过程；同时进一步证明，ｃＡＭＰ本身是参与调节矫治牙齿槽骨组织改建的重要介质。
The aim of this study was, to explore the mechanism of CH ELS promoting bone remodelling of orthodontic tooth in rats. 11 male sprague Dawleg rats was divided into 3 groups. Group I (normal control group) Group Ⅱ(applied force, no injection )Group Ⅲ (applied force, injection). The experimental period was 3 days. The radioimmunoassay (RIA) method were used to investigate the effects of CH ELS on the content of endogenous cAMP in alveolar bone of orthodontic tooth in rats. Results indicate that CH ELS has no significant effects on endogenous cAMP in alveolar bone of orthodontic tooth, perhaps, cAMP were not involved to regulate the mechanism of CH ELS promoting bone remodelling. To explore the mechanism of bone remodelling of orthodontic tooth is more significant in orthodontic clinic.
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
1997年第1期40-42,共3页
Chinese Journal of Stomatology
基金
国家自然科学基金
关键词
中草药
牙畸形
CAMP
黔岭藿
牙槽骨
Drugs, Chinese herbal Tooth abnormalities Nucleotides, cyclic
