摘要
骨形态发生蛋白-7(BMP-7)作为一种成骨蛋白,属于转化生长因子β(TGF-β)超家族中的一员,是维持肾脏正常发育的重要因子。近年来国内外研究表明,BMP-7在慢性肾脏疾病中有重要的抗纤维化作用。本文主要就BMP-7在糖尿病肾病发生、发展中的作用做一综述。
As an osteogenic protein,bone morphorgenetic protein-7（BMP-7） is a member of the transforming growth factor-beta（TGF-β） superfamily,which plays an important role in the normal growth of kidney.In recent years domestic and international researches have showed that BMP-7 plays an important role in terms of anti-fibrosis in chronic kidney disease.The paper mainly summarizes the role of BMP-7 in the occurrence and development of diabetic nephropathy.
出处
《中国全科医学》
CAS
CSCD
北大核心
2013年第3期240-242,共3页
Chinese General Practice
关键词
骨形态发生蛋白-7
转化生长因子Β
糖尿病
糖尿病肾病
Bone morphorgenetic protein 7
Transforming growth factor beta
Diabetes mellitus
Diabetic nephropathies
