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MMP-7与肺纤维化 被引量:7

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摘要 特发性肺纤维化(Idiopathicpulmonaryfibrosis,IPF)是一种发病原因不明,发病机制不清,病理表现为普通型间质性肺炎(usualinterstitialpneumonia,UIP)的进行性发展的致死性疾病。随着细胞生物学及分子生物学的发展,认为肺纤维化发病机制的共同特征可能是体内细胞外基质(extracellular matrjx,ECM)的合成和降解的代谢失衡,即ECM过多的沉积在肺组织内并逐渐演变成为肺间质纤维化。
作者 向敏 赵勇
出处 《临床肺科杂志》 2013年第3期525-527,共3页 Journal of Clinical Pulmonary Medicine
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参考文献21

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