摘要
目的探讨阿托伐他汀钙对冠心病充血性心力衰竭(CHF)患者心功能的影响。方法 79例冠心病心力衰竭患者为2组,对照组按心衰治疗常规进行治疗,实验组加用阿托伐他汀钙治疗。治疗6个月后,比较两组患者心功能变化。结果实验组患者治疗6个月后左心射血分数(LVEF)、左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)改善较对照组明显,差异有统计学意义(t=8.3、5.3、4.0,P<0.05)。实验组心功能改善率(80.0%)明显高于对照组(53.9%),差异有统计学意义(χ2=6.12,P<0.05)。结论阿托伐他汀钙应用于冠心病心力衰竭患者,可明显改善患者的心功能。
Objective To explore the effect of cardiac function of atorvastatin calcium in patients with CHF.Methods Divided 79 cases of patients with CHF into two groups randomly,while control group received conventional treatment and experimental group received atorvastatin calcium else.After treated six months,compared the cardiac function of two groups.Results After treated six months,LVEF,LVEDD and LVESD of experimental group were improved more significanter than control group(t=8.3,5.3,4.0,P0.05).Improve rate of cardiac function of experimental group(80%) was higher than control group(53.9%),and a significant difference was observed(χ2=6.12,P0.05).Conclusion For patients with CHF,atorvastatin calcium can significantly improve the cardiac function.
出处
《中国医药指南》
2012年第35期425-426,共2页
Guide of China Medicine
关键词
阿托伐他汀钙
冠心病
心力衰竭
心功能
Atorvastatin calcium
Coronary heart disease
Congestive heart failure
Cardiac function