期刊文献+

阿托伐他汀对慢性充血性心力衰竭心功能及肿瘤坏死因子的影响 被引量:6

下载PDF
导出
摘要 目的:观察阿托伐他汀在慢性充血性心力衰竭治疗中的作用。方法:入选62例心力衰竭患者,随机分成观察组(32例)和对照组(30例)。所有心力衰竭患者均常规治疗,观察组加用阿托伐他汀10 mg/d,治疗8周,治疗前后查血脂、肿瘤坏死因子(TNF-α),测定心功能(LVEF)。结果:两组患者治疗后LVEF上升,TNF-α下降,观察组LVEF上升,TNF-α下降与对照组比较差异有统计学意义(P<0.05)。结论:心力衰竭患者加用阿托伐他汀治疗可进一步改善心功能并降低TNF-α。
出处 《南通大学学报(医学版)》 2008年第2期114-115,共2页 Journal of Nantong University(Medical sciences)
  • 相关文献

参考文献6

  • 1[1]Recchia FA,Bemstein RD,Sehgal PB,et al.Cytokines are a requisite part of the Pathophysiology Leading to Cardiac deeompensation[J].Proc Soc Exp Biol Med,2000,223(1):47-52. 被引量:1
  • 2[2]Mann DL Recent insights into the role of tumor necrosis factor in the failure heart[J].Heart Fail Rw,2001,6(2):71-80. 被引量:1
  • 3[3]Yilmaz MB,Guray U,Guyay Y,et al,Lipid profile of pa-tients with aortis stenosis mighf be predictive of rate of progression[J].Am Heart J,2004,147(5):761-763. 被引量:1
  • 4[4]Sola s,Mir MQ,Lerakis S,et al,Atorvastatin improves Left Vetricular systolil function and serum Markers of inflam-marion in nonischemic heart failure[J].J Am Coll Cardiol,2006,47(2):332-337. 被引量:1
  • 5[5]Tousoulis D,Antoniades C,Bosinakou E,et al,Effects of atorvastatin on reactive hyperemia and inflammatory pro-cess in patients with Congestive heart failure[J].Atheroscl-erosis,2005,178(2):359-363. 被引量:1
  • 6[6]Lou JD,zhang WW,zhang GP,et al.Simvastain inhibits noradrenaline in dueed hypertrophy of cultured neonatal rat Cardiomyocytes[J].Br J Pharm aeol,2001,132(1):159-164. 被引量:1

同被引文献47

  • 1付启科,傅春江,王旭开,杨成明,王红勇,张晔,石伟彬.坎地沙坦与苯那普利对充血性心力衰竭患者心功能及神经内分泌激素的影响研究[J].现代医药卫生,2006,22(21):3236-3237. 被引量:8
  • 2Yilmaz MB,Guray U,Guyay Y,et al.Lipid profile of patients with aortis stenosis mighf be predictive of rate of progression[J].Am Heart J,2004,147(5):761-763. 被引量:1
  • 3Go AS,Lee WY,Yang J,et al.Statin therapy and risks for death and hopitalization in chronic heart filure[J].JAMA,2006,296(17):2105-2111. 被引量:1
  • 4Goldberger JJ,Subacius H,Schaechter A,et al.Effects of statin therapy on arrhythmic events and survival in patients with nonischemic dilated cardiomyopathy[J].J Am Coll Cardiol,2006,48(6):1228-1233. 被引量:1
  • 5Sola S,Mir MQ,Lerakis S,et al.Atorvastatin improves left vetricular systolil function and serum markers of inflammation in nonischemic heart failure[J].J Am Coll Cardiol,2006,47(2):332-337. 被引量:1
  • 6Tousoulis D,Antoniades C,Bosinakou E,et al.Effects of atorvastatin on reactive hyperemia and inflammatory process in patients with congestive heart failure[J].Atherosclerosis,2005,178(2):359-363. 被引量:1
  • 7Go AS, Lee wY, Yang Jet. Statin therapy and risks for death hopitalization in chronic heart filure [ J ]. JAMA ,2006 ,296 ( 17 ) : 105 - 111. 被引量:1
  • 8Walter DH, Fichtlschere S, Britten MB,et al. Benefits of immediate initiation of statin the rapy following successful coronary stent implantation in patients with stable and unstable angina pectoris and Q-wave acute myocardial infarction [J]. Am J Cardiol, 2002,89 : 1-6. 被引量:1
  • 9Colhoun HM, Betteridge D J, Durrington PN, et al. Effects of atorvastatin on kidney outcomes and cardiovascular disease in patients with diabetes:an analysis from the Collaborative Atorvastatin Diabetes Study (CARDS)[J]. Am J Kidney Dis,2009,54: 810-819. 被引量:1
  • 10Cipolla MJ,Bishop N,Vinke RS,et al. PPAR{gamma}activation prevents hypertensive remodeling of cerebral arterises and improves vascular function in female rats [J]. Strke,2010,41: 1266-1270. 被引量:1

引证文献6

二级引证文献66

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部