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B型利钠肽和高敏C反应蛋白对左室舒张功能不全的诊断价值 被引量:6

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摘要 目的:评价B型利钠肽和高敏C反应蛋白(Hs-CRP)在舒张性心功能不全的严重分级中的临床价值。方法:入选心内科门诊及病房的患者,使用组织多普勒成像(TDI)测量的E/e′比值反映左心室舒张功能不全(LVFP)水平,E/A比值和DT进行左室舒张功能障碍程度分级,分析Hs-CRP和B型利钠肽(BNP)与E/e′比值的相关性,使用ROC曲线分析评价指标评价左室充盈压升高的敏感性和特异性。结果:Hs-CRP和BNP与E/e′比值呈正相关,差异具有统计学意义(P<0.05),在鉴别假性正常充盈功能和检测LVFP升高(E/e′比值>15)方面,Hs-CRP与BNP相比,具有更高的敏感性,但特异性较低。结论:结合Hs-CRP和BNP可提高诊断的灵敏度,对于左室舒张功能障碍的早期诊断具有临床意义。
出处 《实用医学杂志》 CAS 北大核心 2012年第20期3400-3402,共3页 The Journal of Practical Medicine
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