摘要
目的了解宿松县人民医院常见细菌的分布特点及耐药现状,为基层医院临床合理使用抗菌药物提供依据。方法 2010年9月—2012年3月在宿松县人民医院共分离细菌1 092株,用ATB Expression全自动细菌鉴定仪进行菌种鉴定及药敏试验,并分析结果。结果临床分离的1 092株细菌中革兰阴性菌761株占69.69%,革兰阳性菌331株占30.31%。检出率在前7位的细菌分别为大肠埃希菌(390株/35.71%)、表皮葡萄球菌(125株/11.45%)、金黄色葡萄球菌(80株/7.33%)、铜绿假单胞菌(67株/6.14%)、肺炎克雷伯菌(56株/5.13%)、溶血葡萄球菌(50株/4.58%)以及阴沟肠杆菌(21株/1.92%)。革兰阴性菌和革兰阳性菌均对基层医院常用抗菌药物存在不同程度的耐药。革兰阴性杆菌对碳青霉烯类抗菌药物最敏感,未检测到对万古霉素中介或耐药的葡萄球菌。结论基层医院应加强对细菌耐药性监测,及时掌握本地区细菌对抗菌药物耐药的最新动态,指导临床医生合理应用抗菌药物,遏制耐药菌的产生和传播。
Objective To investigate the distribution and resistance of bacterial isolates collected in Susong People＇s Hospital,to provide a reasondble basis,for the clinical use of antibacterial drugs.Methods Totally 1 092 bacterial isolates collected in Susong People＇s Hospital from September 2010 to March 2012 were subjected to identification and susceptibility testing by ATB Expression automatic detection machine.Results Of the 1 092 isolates,761（69.69%） were found to be gram-negative bacterium and 331（30.31%） were gram-positive bacteria.The top seven bacteria identified were Escherichia coli（390/35.71%）,Staphylococcus epidermidis（125/11.45%）,Staphylococcus aureus（80/7.33%）,Pseudomonas aeruginosa（67/6.14%）,Klebsiella pneumonia（56/5.13%）,Staphylococcus haemolyticus（50/4.58%） and Enterobacter cloacae（21/1.92%）.Each kind of these common pathogens had antibiotic resistance to varying degree.Carbapenems were the most effective antimicrobial agents against gram-negative bacterium and no vancomycin-resistant Staphylococcus aureus were detected in this study.Conclusions Primary hospitals should intensify the monitoring to resistant bacteria and master the freshest developments of the drug-resistance without delay which provides guidance for the wise selection of antibiotic and curb the occurrence and prevalence of drug-resistant bacteria.
出处
《安徽医药》
CAS
2012年第12期1892-1894,共3页
Anhui Medical and Pharmaceutical Journal
关键词
革兰阳性菌
革兰阴性菌
耐药监测
Gram-positive bacteria
Gram-negative bacteria
drug resistance surveillance
