摘要
目的:了解女性泌尿生殖道支原体感染情况及药物敏感性,为临床合理用药提供依据。方法:采用支原体培养、鉴定药敏试剂盒,对送检的1 556例泌尿生殖道标本进行支原体培养和药敏试验,并对结果进行分析。结果:1 556例送检标本中支原体培养阳性858例,阳性率为55.14%;其中解脲支原体(Uu)单一感染634例,占总阳性的73.89%,人型支原体(Mh)单项感染58例,占总阳性的6.76%,Uu和Mh混合感染166例,占总阳性的19.35%;支原体对12种抗菌药的敏感率由高到低依次为:交沙霉素(96.15%)、美满霉素(87.18%)、强力霉素(80.19%)、克拉霉素(70.16%)、环脂红霉素(65.73%)、阿奇霉素(59.21%)、罗红霉素(57.11%)、甲砜霉素(48.72%)、红霉素(43.12%)、加替沙星(39.86%)、左氧氟沙星(27.74%)、环丙沙星(26.34%)。结论:解脲支原体是女性泌尿生殖道感染最常见的病原体,多发于21～40岁年龄段,临床首选药物依次为交沙霉素、美满霉素、强力霉素。
Objective To understand the infection and drug susceptibility of region＇s female urogenital mycoplasma,to provide a basis for clinical medication. Method Genitourinary tract specimen of 1556 cases who were in gynecology clinic of our hospital were proceeded mycoplasma culture and susceptibility testing,and the results were analyzed. Results Mycoplasma culture was positive in 858 cases of 1556 cases,and the positive rate was 55. 14% ;Ureaplasma urealyticum （Uu） single infection was in 634 cases,and accounting for 73. 89% of the positive, Mycoplasma hominis （Mh） single infection was in 58 cases, and the total positive was 6. 76%, Uu and Mh mixed infection was in 166 cases,accounting for 19. 35% of the positive; Mycoplasma sensitive of 12 kinds of antimicrobial agents was as follows with the order from high to low ：josamycin （ 96. 15% ）, minocycline （ 87. 18% ）, doxycycline （ 80. 19% ）, clarithromycin （70. 16% ）, ringgrease erythro- mycin （65.73%） ,azithromycin （59. 21% ） ,roxithromycin （57.11%） ,thiamphenicol （48. 72% ）, erythromycin （43. 12% ） ,gatifloxacin gatifloxacin （39. 86% ） levofloxacin （ 27.74% ）, ciprofloxacin （ ：26. 34% ）. Conclusion Uu is the most common pathogens of the female genitourinary tract infection, mainly in the 21 - 40 years old age group, the clinical drug of choice followed by josamycin, minocycline, doxy- cycline.
出处
《吉林医学》
CAS
2012年第34期7433-7434,共2页
Jilin Medical Journal
关键词
泌尿生殖道
支原体
药物敏感试验
Genitourinary tract
Mycoplasma
Drug sensitivity test
