摘要
目的调查本地区女性泌尿生殖道支原体感染状况及对常用抗菌药物的耐药性,为临床合理治疗提供依据。方法回顾性分析2011年-2015年于本院妇科就诊的4 942例患者支原体培养、鉴定及药敏试验资料。结果服务业从业者、小学及以下者、19岁～30岁患者支原体感染率最高,差异均有统计学意义（P〈0.05）。总感染率为48.9%,连续5年支原体的阳性检出率总体呈上升趋势,主要以解脲脲原体（Uu）单独感染为主,占74.6%,3种感染类型对罗红霉素、阿奇霉素、氧氟沙星和左氧氟沙星的耐药率均〉40.0%,对美满霉素、强力霉素和交沙霉素保持良好的抗菌活性,耐药率均〈10.0%。结论支原体感染与职业、文化程度、年龄等因素有关,本地区女性泌尿生殖道支原体感染率呈逐年上升趋势,并以Uu单独感染为主,治疗支原体感染应注意流行病学因素和药敏试验结果,美满霉素、强力霉素和交沙霉素可作为首选经验用药。
Objective To investigate the Mycoplasma infection status in the local women and the drug resistance of the commonly used antibiotics,so as to provide basis for clinical rational treatment. Methods Retrospective analysis was conducted on the Mycoplasma culture,identification and drug sensitivity test data of 4 942 gynecological patients from 2011 to 2015 in our hospital. Results The highest infection rate of Mycoplasma was obtained in service industry practitioners,primary school and the following,19 years old to 30 years old patients,and the differences were statistically significant（ P〈0. 05）. The total infection rate was 48. 9%,the positive detection rate of Mycoplasma in 5 consecutive years showed a rising trend,mainly in Uu single infection,accounting for 74. 6%; three types of infection resistance to roxithromycin,azithromycin,ofloxacin and levofloxacin were 40. 0%,and showed good antibacterial activity to minocycline,doxycycline and josamycin maintain,with the resistance rate 10. 0%. Conclusion Mycoplasma infection was related to occupation,education,age and other factors,and the infection rate of Mycoplasma in the female urinary tract in the local area increases year by year,with Uu single infection as dominant;the epidemiological factors and drug sensitivity test results should be paid attention to in the treatment of Mycoplasma infection,and minocycline,doxycycline and josamycin can be used as the preferred antibiotics in the treatment of Mycoplasma infection.
出处
《中国卫生检验杂志》
CAS
2016年第17期2561-2563,共3页
Chinese Journal of Health Laboratory Technology
关键词
泌尿生殖道
支原体
耐药性
Urogenital tract
Mycoplasma
Drug resistance
