摘要
目的探讨新生儿甲状腺功能低下筛查对早发现和早诊断的作用。方法对2009～2011年的134604例新生儿甲状腺水平进行检测,再检测召回的可疑患儿的血清甲状腺功能,对其进行确诊,将确诊的74例患儿作为观察组,再随机选取正常健康的74例新生儿作为健康对照组,对筛查的基本情况和两组研究对象的早期临床症状进行观察。结果检出可疑甲状腺功能低下患儿共666例,召回397例患儿,总召回率为60.04%,确诊为甲状腺功能低下的患儿74例,总发病率为5.5/10000;观察组新生儿患者脐疝、黄疸延迟、皮肤毛发干燥和粘液性水肿的发生率分别为45.95%、55.41%、17.57%和18.92%,均明显高于健康对照组(14.86%、28.37%、0和0),差异具有统计学意义(P<0.05)。结论在人群中开展新生儿甲状腺功能低下筛查,可以帮助早期发现和诊断疾病,有效提高新生儿的健康素质。
Objective To investigate the neonatal hypothyroid screening on early detection and early diagnosis in the presence of role. Methods From 2009 to 2011 of 134604 cases of neonatal thyroid levels were detected, and detection recall suspicious patients serum thyroid function, carries on the diagnosis to be confirmed, 74 cases as the observation group, and then randomLy selected normal healthy 74 newborns as healthy control group, the screening and the basic situation of the two group study early clinical symptom observation. Results The detection of suspected hypothyroidism in all 666 cases, 397 cases of total recall, recall rate of 60.04%, diagnosed with hypothyroidism in 74 cases, the total incidence of 5.5/10000; observationgroup, jaundice, neonatal umbilical hernia in patients with delayed skin and hair drying and mucinous edema rate were 45.95%, 55.41%, in 17.57% and 18.92%, were significantly higher than those in the control group （ 14.86%, 28.37%, 0 and 0）, the difference was statistically significant（P〈0.05）. Conclusion In a population of neonatal screening for congenital hypothyroidism, can help in the early detection and diagnosis of the disease, effectively improve the health quality of newborn.
出处
《当代医学》
2012年第36期5-6,共2页
Contemporary Medicine
关键词
新生儿
甲状腺功能低下筛查
早发现
早诊断
Newborn
Screening for congenital hypothyroidism
Early detection
Early diagnosis
