摘要
目的探讨老年人原发性脑出血的重要原因,分析脑血管淀粉样变(CAA)在老年人原发性脑出血(PICH)发病中的致病作用。方法选取过去5年中急性颅内血管淀粉变性脑出血的病人42例。对其临床资料、影像特征、病理资料及治疗结果等进行分析。结果脑血管淀粉样变所致脑出血在60岁以上原发性脑出血人群中超过30%。其临床、放射影像学和病理学上具有一定的特点,包括脑出血发病率随年龄增加而增高,脑叶出血好发,血肿量大且呈分叶状,出血易破入蛛网膜下腔和脑室等。结论老年人原发性脑出血排除高血压后首先需要考虑脑血管定汾样变脑出血。
Objective To discuss the important cause of primary intracerebral haemorrhage （PICH） in older people and analyzing the role of cerebral amyloid angiopathy（CAA） which caused primary intracerebral haemorrhage in older people. Methods The clinical and imaging characteristics, pathological data and treatment results of 42 patients with PICH due to CAA in the past 5 years were retrospectively analysed. Results PICH due to CAA accounted for ＋ 30% of all types PICH in old people. It has clinical radiological and pathological characteristics, including the incidence of PICH increases with age, multiplicity of haeinorrhage,and repeated episodes,lobulated appearance,rupture into the subarachnoid space and secondary intraventricular haemorrhage from the lobar haemorrhage. Conclusion Excluding the possibility of hypertension, CAA should be cons（dered as the very important cause of primary intracerebral haemorrhage in older people.
出处
《临床神经外科杂志》
CAS
2012年第5期286-287,共2页
Journal of Clinical Neurosurgery
关键词
脑出血
血管淀粉样变性
高血压
intracerebral haemorrhage
cerebral amyloid angiopathy
hypertension
